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Modeling colorectal cancer progression reveals niche-dependent clonal selection

Colorectal cancer (CRC) is among the deadliest cancers worldwide, with metastasis being the main cause of patient mortality. During CRC progression the complex tumor ecosystem changes in its composition at virtually every stage. However, clonal dynamics and associated niche-dependencies at these sta...

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Main Authors: Vaquero Siguero, Nuria (Author) , Schleußner, Nikolai (Author) , Volk, Julia (Author) , Mastel, Manuel (Author) , Meier, Jasmin (Author) , Jackstadt, René-Filip (Author)
Format: Article (Journal)
Language:English
Published: 31 August 2022
In: Cancers
Year: 2022, Volume: 14, Issue: 17, Pages: 1-19
ISSN:2072-6694
DOI:10.3390/cancers14174260
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers14174260
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/14/17/4260
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Author Notes:Nuria Vaquero-Siguero, Nikolai Schleussner, Julia Volk, Manuel Mastel, Jasmin Meier, Rene Jackstadt

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