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Randomized controlled phase I/II study to investigate immune stimulatory effects by low dose radiotherapy in primarily operable pancreatic cancer

The efficiencies of T cell based immunotherapies are affected by insufficient migration and activation of tumor specific effector T cells in the tumor. Accumulating evidence exists on the ability of ionizing radiation to modify the tumor microenvironment and generate inflammation. The aim of this ph...

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Main Authors: Timke, Carmen (Author) , Schmitz-Winnenthal, Friedrich Hubertus (Author) , Klug, Felix (Author) , Röder, Falk (Author) , Bonertz, Andreas (Author) , Reißfelder, Christoph (Author) , Rochet, Nathalie (Author) , Koch, Moritz (Author) , Tjaden, Christin (Author) , Büchler, Markus W. (Author) , Debus, Jürgen (Author) , Werner, Jens (Author) , Beckhove, Philipp (Author) , Weitz, Jürgen (Author) , Huber, Peter E. (Author)
Format: Article (Journal)
Language:English
Published: 13 April 2011
In: BMC cancer
Year: 2011, Volume: 11, Pages: 1-7
ISSN:1471-2407
DOI:10.1186/1471-2407-11-134
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-11-134
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Author Notes:Carmen Timke, Hubertus Schmitz Winnenthal, Felix Klug, Falk FF Roeder, Andreas Bonertz, Christoph Reissfelder, Nathalie Rochet, Moritz Koch, Christine Tjaden, Markus W Buechler, Juergen Debus, Jens Werner, Philipp Beckhove, Jürgen Weitz and Peter E Huber

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