Cover Image

Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer

Background: Elevated serum concentrations of insulin-like growth factor (IGF)-I have been associated with increased risk of developing breast cancer. Previously, we reported a similar association in samples obtained during pregnancy. This study was conducted to further characterize the association o...

Full description

Saved in:
Bibliographic Details
Main Authors: Toriola, Adetunji T. (Author) , Lundin, Eva (Author) , Schöck, Helena (Author) , Grankvist, Kjell (Author) , Pukkala, Eero (Author) , Chen, Tianhui (Author) , Zeleniuch-Jacquotte, Anne (Author) , Toniolo, Paolo (Author) , Lehtinen, Matti (Author) , Surcel, Helja-Marja (Author) , Lukanova, Annekatrin (Author)
Format: Article (Journal)
Language:English
Published: August 07 2011
In: Cancer epidemiology, biomarkers & prevention
Year: 2011, Volume: 20, Issue: 8, Pages: 1798-1801
ISSN:1538-7755
DOI:10.1158/1055-9965.EPI-11-0441
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/1055-9965.EPI-11-0441
Get full text
Author Notes:Adetunji T. Toriola, Eva Lundin, Helena Schock, Kjell Grankvist, Eero Pukkala, Tianhui Chen, Anne Zeleniuch-Jacquotte, Paolo Toniolo, Matti Lehtinen, Helja-Marja Surcel, and Annekatrin Lukanova

MARC

LEADER 00000caa a2200000 c 4500
001 1822642949
003 DE-627
005 20230710102451.0
007 cr uuu---uuuuu
008 221116s2011 xx |||||o 00| ||eng c
024 7 |a 10.1158/1055-9965.EPI-11-0441  |2 doi 
035 |a (DE-627)1822642949 
035 |a (DE-599)KXP1822642949 
035 |a (OCoLC)1389751365 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Toriola, Adetunji T.  |e VerfasserIn  |0 (DE-588)1162977086  |0 (DE-627)1027075363  |0 (DE-576)507727770  |4 aut 
245 1 0 |a Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer  |c Adetunji T. Toriola, Eva Lundin, Helena Schock, Kjell Grankvist, Eero Pukkala, Tianhui Chen, Anne Zeleniuch-Jacquotte, Paolo Toniolo, Matti Lehtinen, Helja-Marja Surcel, and Annekatrin Lukanova 
264 1 |c August 07 2011 
300 |a 4 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 16.11.2022 
520 |a Background: Elevated serum concentrations of insulin-like growth factor (IGF)-I have been associated with increased risk of developing breast cancer. Previously, we reported a similar association in samples obtained during pregnancy. This study was conducted to further characterize the association of IGF-I during pregnancy with maternal breast cancer risk.Methods: A case-control study was nested within the Finnish Maternity Cohort. The study was limited to primiparous women younger than 40 years, who donated blood samples during early (median, 12 weeks) pregnancy and delivered a single child at term. Seven hundred nineteen women with invasive breast cancer were eligible. Two controls (n = 1,434) were matched with each case on age and date at blood donation. Serum IGF-I concentration was measured using an Immulite 2000 analyzer. Conditional logistic regression was used to estimate ORs and 95% CIs.Results: No significant associations were observed between serum IGF-I concentrations and breast cancer risk in both the overall analysis (OR, 1.08; 95% CI, 0.80-1.47) and in analyses stratified by histologic subtype, lag time to cancer diagnosis, age at pregnancy, or age at diagnosis.Conclusion: There was no association between IGF-I and maternal breast cancer risk during early pregnancy in this large nested case-control study.Impact: Serum IGF-I concentrations during early pregnancy may not be related to maternal risk of developing breast cancer. Cancer Epidemiol Biomarkers Prev; 20(8); 1798-801. ©2011 AACR. 
700 1 |a Lundin, Eva  |e VerfasserIn  |4 aut 
700 1 |a Schöck, Helena  |d 1971-  |e VerfasserIn  |0 (DE-588)134304756  |0 (DE-627)566673630  |0 (DE-576)278648851  |4 aut 
700 1 |a Grankvist, Kjell  |e VerfasserIn  |4 aut 
700 1 |a Pukkala, Eero  |e VerfasserIn  |4 aut 
700 1 |a Chen, Tianhui  |e VerfasserIn  |4 aut 
700 1 |a Zeleniuch-Jacquotte, Anne  |e VerfasserIn  |4 aut 
700 1 |a Toniolo, Paolo  |e VerfasserIn  |4 aut 
700 1 |a Lehtinen, Matti  |e VerfasserIn  |4 aut 
700 1 |a Surcel, Helja-Marja  |e VerfasserIn  |4 aut 
700 1 |a Lukanova, Annekatrin  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Cancer epidemiology, biomarkers & prevention  |d Philadelphia, Pa. : AACR, 1991  |g 20(2011), 8, Seite 1798-1801  |h Online-Ressource  |w (DE-627)325489912  |w (DE-600)2036781-8  |w (DE-576)094752745  |x 1538-7755  |7 nnas  |a Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer 
773 1 8 |g volume:20  |g year:2011  |g number:8  |g pages:1798-1801  |g extent:4  |a Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer 
856 4 0 |u https://doi.org/10.1158/1055-9965.EPI-11-0441  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20221116 
993 |a Article 
994 |a 2011 
998 |g 134304756  |a Schöck, Helena  |m 134304756:Schöck, Helena  |p 3 
999 |a KXP-PPN1822642949  |e 4212213451 
BIB |a Y 
SER |a journal 
JSO |a {"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["2036781-8"],"eki":["325489912"],"issn":["1538-7755"]},"origin":[{"publisherPlace":"Philadelphia, Pa.","dateIssuedDisp":"1991-","publisher":"AACR","dateIssuedKey":"1991"}],"name":{"displayForm":["American Association for Cancer Research"]},"part":{"text":"20(2011), 8, Seite 1798-1801","volume":"20","extent":"4","year":"2011","pages":"1798-1801","issue":"8"},"pubHistory":["1.1991/92 -"],"recId":"325489912","language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 08.06.2023","Fortsetzung der Druck-Ausgabe"],"disp":"Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancerCancer epidemiology, biomarkers & prevention","title":[{"title_sort":"Cancer epidemiology, biomarkers & prevention","title":"Cancer epidemiology, biomarkers & prevention"}]}],"physDesc":[{"extent":"4 S."}],"id":{"doi":["10.1158/1055-9965.EPI-11-0441"],"eki":["1822642949"]},"origin":[{"dateIssuedKey":"2011","dateIssuedDisp":"August 07 2011"}],"name":{"displayForm":["Adetunji T. Toriola, Eva Lundin, Helena Schock, Kjell Grankvist, Eero Pukkala, Tianhui Chen, Anne Zeleniuch-Jacquotte, Paolo Toniolo, Matti Lehtinen, Helja-Marja Surcel, and Annekatrin Lukanova"]},"language":["eng"],"recId":"1822642949","type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 16.11.2022"],"title":[{"title_sort":"Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer","title":"Circulating insulin-like growth factor-I in pregnancy and maternal risk of breast cancer"}],"person":[{"given":"Adetunji T.","family":"Toriola","role":"aut","display":"Toriola, Adetunji T.","roleDisplay":"VerfasserIn"},{"given":"Eva","family":"Lundin","role":"aut","display":"Lundin, Eva","roleDisplay":"VerfasserIn"},{"family":"Schöck","given":"Helena","display":"Schöck, Helena","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Grankvist, Kjell","roleDisplay":"VerfasserIn","role":"aut","family":"Grankvist","given":"Kjell"},{"given":"Eero","family":"Pukkala","role":"aut","display":"Pukkala, Eero","roleDisplay":"VerfasserIn"},{"family":"Chen","given":"Tianhui","display":"Chen, Tianhui","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","display":"Zeleniuch-Jacquotte, Anne","roleDisplay":"VerfasserIn","given":"Anne","family":"Zeleniuch-Jacquotte"},{"given":"Paolo","family":"Toniolo","role":"aut","display":"Toniolo, Paolo","roleDisplay":"VerfasserIn"},{"given":"Matti","family":"Lehtinen","role":"aut","roleDisplay":"VerfasserIn","display":"Lehtinen, Matti"},{"family":"Surcel","given":"Helja-Marja","roleDisplay":"VerfasserIn","display":"Surcel, Helja-Marja","role":"aut"},{"role":"aut","display":"Lukanova, Annekatrin","roleDisplay":"VerfasserIn","given":"Annekatrin","family":"Lukanova"}]} 
SRT |a TORIOLAADECIRCULATIN0720 

Similar Items