Drug-resistant malaria: molecular mechanisms and implications for public health
Resistance to antimalarial drugs has often threatened malaria elimination efforts and historically has led to the short-term resurgence of malaria incidences and deaths. With concentrated malaria eradication efforts currently underway, monitoring drug resistance in clinical settings complemented by...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
23 April 2011
|
| In: |
FEBS letters
Year: 2011, Volume: 585, Issue: 11, Pages: 1551-1562 |
| ISSN: | 1873-3468 |
| DOI: | 10.1016/j.febslet.2011.04.042 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.febslet.2011.04.042 |
| Author Notes: | Ines Petersen, Richard Eastman, Michael Lanzer |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1823826954 | ||
| 003 | DE-627 | ||
| 005 | 20230710101416.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 221129s2011 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.febslet.2011.04.042 |2 doi | |
| 035 | |a (DE-627)1823826954 | ||
| 035 | |a (DE-599)KXP1823826954 | ||
| 035 | |a (OCoLC)1389745006 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Petersen, Ines |e VerfasserIn |0 (DE-588)1129194027 |0 (DE-627)883833042 |0 (DE-576)486258327 |4 aut | |
| 245 | 1 | 0 | |a Drug-resistant malaria |b molecular mechanisms and implications for public health |c Ines Petersen, Richard Eastman, Michael Lanzer |
| 264 | 1 | |c 23 April 2011 | |
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.11.2022 | ||
| 520 | |a Resistance to antimalarial drugs has often threatened malaria elimination efforts and historically has led to the short-term resurgence of malaria incidences and deaths. With concentrated malaria eradication efforts currently underway, monitoring drug resistance in clinical settings complemented by in vitro drug susceptibility assays and analysis of resistance markers, becomes critical to the implementation of an effective antimalarial drug policy. Understanding of the factors, which lead to the development and spread of drug resistance, is necessary to design optimal prevention and treatment strategies. This review attempts to summarize the unique factors presented by malarial parasites that lead to the emergence and spread of drug resistance, and gives an overview of known resistance mechanisms to currently used antimalarial drugs. | ||
| 650 | 4 | |a Animals | |
| 650 | 4 | |a Antimalarials | |
| 650 | 4 | |a Drug Resistance | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Malaria | |
| 650 | 4 | |a Plasmodium vivax | |
| 650 | 4 | |a Public Health | |
| 700 | 1 | |a Eastman, Richard |e VerfasserIn |0 (DE-588)1274108993 |0 (DE-627)1823828256 |4 aut | |
| 700 | 1 | |a Lanzer, Michael |e VerfasserIn |0 (DE-588)1065643314 |0 (DE-627)816506736 |0 (DE-576)165563826 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |a Vereinigung der Europäischen Biochemischen Gesellschaften |t FEBS letters |d Chichester : Wiley, 1968 |g 585(2011), 11, Seite 1551-1562 |h Online-Ressource |w (DE-627)253779669 |w (DE-600)1460391-3 |w (DE-576)07279383X |x 1873-3468 |7 nnas |
| 773 | 1 | 8 | |g volume:585 |g year:2011 |g number:11 |g pages:1551-1562 |g extent:12 |a Drug-resistant malaria molecular mechanisms and implications for public health |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.febslet.2011.04.042 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20221129 | ||
| 993 | |a Article | ||
| 994 | |a 2011 | ||
| 998 | |g 1065643314 |a Lanzer, Michael |m 1065643314:Lanzer, Michael |d 910000 |d 911700 |e 910000PL1065643314 |e 911700PL1065643314 |k 0/910000/ |k 1/910000/911700/ |p 3 |y j | ||
| 998 | |g 1129194027 |a Petersen, Ines |m 1129194027:Petersen, Ines |d 910000 |d 911700 |e 910000PP1129194027 |e 911700PP1129194027 |k 0/910000/ |k 1/910000/911700/ |p 1 |x j | ||
| 999 | |a KXP-PPN1823826954 |e 4221610549 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"title":[{"title_sort":"FEBS letters","subtitle":"for the rapid publication of short reports in biochemistry, biophysics, and molecular biology","title":"FEBS letters"}],"disp":"Vereinigung der Europäischen Biochemischen GesellschaftenFEBS letters","note":["Gesehen am 18.12.2019","Fortsetzung der Druck-Ausgabe"],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"253779669","corporate":[{"roleDisplay":"VerfasserIn","display":"Vereinigung der Europäischen Biochemischen Gesellschaften","role":"aut"}],"language":["eng"],"pubHistory":["1.1968 -"],"part":{"year":"2011","pages":"1551-1562","issue":"11","text":"585(2011), 11, Seite 1551-1562","volume":"585","extent":"12"},"name":{"displayForm":["Federation of European Biochemical Societies. Ed. M. Avron [u.a.]"]},"origin":[{"dateIssuedDisp":"1968-","publisher":"Wiley ; North-Holland Publ. Co. ; Elsevier","dateIssuedKey":"1968","publisherPlace":"Chichester ; Amsterdam ; Amsterdam [u.a.]"}],"id":{"zdb":["1460391-3"],"eki":["253779669"],"doi":["10.1002/(ISSN)1873-3468"],"issn":["1873-3468"]},"physDesc":[{"extent":"Online-Ressource"}]}],"physDesc":[{"extent":"12 S."}],"id":{"doi":["10.1016/j.febslet.2011.04.042"],"eki":["1823826954"]},"origin":[{"dateIssuedKey":"2011","dateIssuedDisp":"23 April 2011"}],"name":{"displayForm":["Ines Petersen, Richard Eastman, Michael Lanzer"]},"recId":"1823826954","language":["eng"],"note":["Gesehen am 29.11.2022"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"subtitle":"molecular mechanisms and implications for public health","title":"Drug-resistant malaria","title_sort":"Drug-resistant malaria"}],"person":[{"family":"Petersen","given":"Ines","roleDisplay":"VerfasserIn","display":"Petersen, Ines","role":"aut"},{"given":"Richard","family":"Eastman","role":"aut","display":"Eastman, Richard","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Lanzer, Michael","given":"Michael","family":"Lanzer"}]} | ||
| SRT | |a PETERSENINDRUGRESIST2320 | ||