Association of intraventricular fibrinolysis with clinical outcomes in intracerebral hemorrhage: an individual participant data meta-analysis

Background: - - In patients with intracerebral hemorrhage (ICH), the presence of intraventricular hemorrhage constitutes a promising therapeutic target. Intraventricular fibrinolysis (IVF) reduces mortality, yet impact on functional disability remains unclear. Thus, we aimed to determine the influe...

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Main Authors:	Kuramatsu, Joji Benjamin (Author) , Gerner, Stefan T. (Author) , Ziai, Wendy (Author) , Bardutzky, Jürgen (Author) , Sembill, Jochen A. (Author) , Sprügel, Maximilian I. (Author) , Mrochen, Anne (Author) , Kölbl, Kathrin (Author) , Ram, Malathi (Author) , Avadhani, Radhika (Author) , Falcone, Guido J. (Author) , Selim, Magdy H. (Author) , Lioutas, Vasileios-Arsenios (Author) , Endres, Matthias (Author) , Zweynert, Sarah (Author) , Vajkoczy, Peter (Author) , Ringleb, Peter A. (Author) , Purrucker, Jan (Author) , Volkmann, Jens (Author) , Neugebauer, Hermann (Author) , Erbguth, Frank (Author) , Schellinger, Peter D. (Author) , Knappe, Ulrich J. (Author) , Fink, Gereon R. (Author) , Dohmen, Christian (Author) , Minnerup, Jens (Author) , Reichmann, Heinz (Author) , Schneider, Hauke (Author) , Röther, Joachim (Author) , Reimann, Gernot (Author) , Schwarz, Michael (Author) , Bäzner, Hansjörg (Author) , Claßen, Joseph (Author) , Michalski, Dominik (Author) , Witte, Otto W. (Author) , Günther, Albrecht (Author) , Hamann, Gerhard F. (Author) , Lücking, Hannes (Author) , Dörfler, Arnd (Author) , Ishfaq, Muhammad Fawad (Author) , Chang, Jason J. (Author) , Testai, Fernando D. (Author) , Woo, Daniel (Author) , Alexandrov, Andrei V. (Author) , Staykov, Dimitre (Author) , Goyal, Nitin (Author) , Tsivgoulis, Georgios (Author) , Sheth, Kevin N. (Author) , Awad, Issam A. (Author) , Schwab, Stefan (Author) , Hanley, Daniel F. (Author) , Huttner, Hagen B. (Author) , Rizos, Timolaos (Author)
Format:	Article (Journal)
Language:	English
Published:	6 May 2022
In:	Stroke Year: 2022, Volume: 53, Issue: 9, Pages: 2876-2886
ISSN:	1524-4628
DOI:	10.1161/STROKEAHA.121.038455
Online Access:	kostenfrei kostenfrei
Author Notes:	Joji B. Kuramatsu, MD; Stefan T. Gerner, MD; Wendy Ziai, MD; Jürgen Bardutzky, MD; Jochen A. Sembill, MD; Maximilian I. Sprügel, MD; Anne Mrochen, MD; Kathrin Kölbl, MD; Malathi Ram, PhD; Radhika Avadhani, MS; Guido J. Falcone, MD; Magdy H. Selim, MD; Vasileios-Arsenios Lioutas, MD; Matthias Endres, MD; Sarah Zweynert, MD; Peter Vajkoczy, MD; Peter A. Ringleb, MD; Jan C. Purrucker, MD; Jens Volkmann, MD; Hermann Neugebauer, MD; Frank Erbguth, MD; Peter D. Schellinger, MD; Ulrich J. Knappe, MD; Gereon R. Fink, MD; Christian Dohmen, MD; Jens Minnerup, MD; Heinz Reichmann, MD; Hauke Schneider, MD; Joachim Röther, MD; Gernot Reimann, MD; Michael Schwarz, MD; Hansjörg Bäzner, MD; Joseph Claßen, MD; Dominik Michalski, MD; Otto W. Witte, MD; Albrecht Günther, MD; Gerhard F. Hamann, MD; Hannes Lücking, MD; Arnd Dörfler, MD; Muhammad Fawad Ishfaq, MD; Jason J. Chang, MD; Fernando D. Testai, MD; Daniel Woo, MD; Andrei V. Alexandrov, MD; Dimitre Staykov, MD; Nitin Goyal, MD; Georgios Tsivgoulis, MD; Kevin N. Sheth, MD; Issam A. Awad, MD; Stefan Schwab, MD†; Daniel F. Hanley, MD†; Hagen B. Huttner, MD†, and Collaborators