Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD

In neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), neutrophils are found in CNS lesions. We previously demonstrated that NMOSD neutrophils show functional deficiencies. Thus, we hypothesized that neutrophil accumulation in...

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Main Authors:	Schroeder-Castagno, Maria (Author) , Del Rio-Serrato, Alba (Author) , Wilhelm, Andreas (Author) , Romero-Suarez, Silvina (Author) , Schindler, Patrick (Author) , Alvarez-González, Cesar (Author) , Duchow, Ankelien-Solveig (Author) , Bellmann-Strobl, Judith (Author) , Ruprecht, Klemens (Author) , Hastermann, Maria (Author) , Grütz, Gerald (Author) , Wildemann, Brigitte (Author) , Jarius, Sven (Author) , Schmitz-Hübsch, Tanja (Author) , Paul, Friedemann (Author) , Infante Duarte, Carmen (Author)
Format:	Article (Journal)
Language:	English
Published:	01 October 2022
In:	Journal of neuroinflammation Year: 2022, Volume: 19, Pages: 1-17
ISSN:	1742-2094
DOI:	10.1186/s12974-022-02600-0
Online Access:	kostenfrei
Author Notes:	Maria Schroeder-Castagno, Alba Del Rio-Serrato, Andreas Wilhelm, Silvina Romero-Suárez, Patrick Schindler, Cesar Alvarez-González, Ankelien-Solveig Duchow, Judith Bellmann-Strobl, Klemens Ruprecht, Maria Hastermann, Gerald Grütz, Brigitte Wildemann, Sven Jarius, Tanja Schmitz-Hübsch, Friedemann Paul and Carmen Infante-Duarte