The impact of tumor metabolic activity assessed by 18F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients
Selective uptake of (18)F-fluoro-ethyl-tyrosine (18F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood transcriptome l...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 September 2022
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| In: |
Frontiers in oncology
Year: 2022, Jahrgang: 12, Pages: 1-15 |
| ISSN: | 2234-943X |
| DOI: | 10.3389/fonc.2022.901390 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.3389/fonc.2022.901390 Verlag, lizenzpflichtig, Volltext: https://www.frontiersin.org/articles/10.3389/fonc.2022.901390 
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| Verfasserangaben: | Maria Waltenberger, Jennifer Furkel, Manuel Röhrich, Patrick Salome, Charlotte Debus, Bouchra Tawk, Aoife Ward Gahlawat, Andreas Kudak, Matthias Dostal, Ute Wirkner, Christian Schwager, Christel Herold-Mende, Stephanie E. Combs, Laila König, Jürgen Debus, Uwe Haberkorn, Amir Abdollahi and Maximilian Knoll |
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| 520 | |a Selective uptake of (18)F-fluoro-ethyl-tyrosine (18F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood transcriptome liquid biopsy (WBT lbx) for which we recently reported feasibility to mirror tumor characteristics and response to particle irradiation in recurrent HGG (rHGG). | ||
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