Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity: a 17-year single-center experience

Background: There is no clear consensus on the optimal surgical strategy for providing safe coverage in salvage free flap surgery after total free flap failure. Methods: A retrospective study was conducted to evaluate patients with total failure of the primary free flap in lower extremity reconstruc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Strübing, Felix (VerfasserIn) , Xiong, Lingyun (VerfasserIn) , Bigdeli, Amir K. (VerfasserIn) , Diehm, Yannick (VerfasserIn) , Kneser, Ulrich (VerfasserIn) , Hirche, Christoph (VerfasserIn) , Gazyakan, Emre (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 September 2022
In: Journal of Personalized Medicine
Year: 2022, Jahrgang: 12, Heft: 10, Pages: 1-16
ISSN:2075-4426
DOI:10.3390/jpm12101563
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/jpm12101563
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2075-4426/12/10/1563
Volltext
Verfasserangaben:Felix Struebing, Lingyun Xiong, Amir K. Bigdeli, Yannick Diehm, Ulrich Kneser, Christoph Hirche and Emre Gazyakan

MARC

LEADER 00000caa a2200000 c 4500
001 1826706119
003 DE-627
005 20230426074550.0
007 cr uuu---uuuuu
008 221209s2022 xx |||||o 00| ||eng c
024 7 |a 10.3390/jpm12101563  |2 doi 
035 |a (DE-627)1826706119 
035 |a (DE-599)KXP1826706119 
035 |a (OCoLC)1361669937 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Strübing, Felix  |d 1991-  |e VerfasserIn  |0 (DE-588)1178373967  |0 (DE-627)1049318501  |0 (DE-576)517755017  |4 aut 
245 1 0 |a Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity  |b a 17-year single-center experience  |c Felix Struebing, Lingyun Xiong, Amir K. Bigdeli, Yannick Diehm, Ulrich Kneser, Christoph Hirche and Emre Gazyakan 
264 1 |c 22 September 2022 
300 |a 16 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 09.12.2022 
520 |a Background: There is no clear consensus on the optimal surgical strategy for providing safe coverage in salvage free flap surgery after total free flap failure. Methods: A retrospective study was conducted to evaluate patients with total failure of the primary free flap in lower extremity reconstruction between 2000 and 2017. Results: In a cohort of 1.016 patients, we identified 43 cases of total flap failure (4.2%). A total of 30 patients received a salvage free flap with a success rate of 83.3% (25/30). One patient received a secondary salvage free flap. Overall limb salvage after primary free flap loss was 83.7% (36/43). Conclusions: Microsurgical management of free flap loss in the lower extremity is challenging and requires a decisive re-evaluation of risk factors and alternative strategies. This should include reconsidering the flap choice with a tendency towards traditional and safe workhorse flaps, a low-threshold switch to different recipient vessels, including arteriovenous (AV) loops, bypasses (especially in case of venous insufficiency) and back-up procedures, such as negative pressure wound therapy or dermal regeneration templates with skin grafting in cases of lower demand and critically ill patients. We derived one suggestion from our previous practice: replacing perforator flaps with axial pattern flaps (“safe workhorses”). 
650 4 |a flap failure 
650 4 |a free flap 
650 4 |a limb salvage 
650 4 |a lower extremity 
650 4 |a orthoplastic 
650 4 |a secondary free flap 
650 4 |a tertiary free flap 
700 1 |a Xiong, Lingyun  |e VerfasserIn  |4 aut 
700 1 |a Bigdeli, Amir K.  |e VerfasserIn  |4 aut 
700 1 |a Diehm, Yannick  |d 1991-  |e VerfasserIn  |0 (DE-588)1128238608  |0 (DE-627)882677144  |0 (DE-576)485761629  |4 aut 
700 1 |a Kneser, Ulrich  |d 1972-  |e VerfasserIn  |0 (DE-588)123065119  |0 (DE-627)706147219  |0 (DE-576)293539987  |4 aut 
700 1 |a Hirche, Christoph  |e VerfasserIn  |0 (DE-588)1074918878  |0 (DE-627)832738484  |0 (DE-576)414117387  |4 aut 
700 1 |a Gazyakan, Emre  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Journal of Personalized Medicine  |d Basel : MDPI, 2011  |g 12(2022), 10, Artikel-ID 1563, Seite 1-16  |h Online-Ressource  |w (DE-627)71862713X  |w (DE-600)2662248-8  |w (DE-576)365413666  |x 2075-4426  |7 nnas  |a Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity a 17-year single-center experience 
773 1 8 |g volume:12  |g year:2022  |g number:10  |g elocationid:1563  |g pages:1-16  |g extent:16  |a Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity a 17-year single-center experience 
856 4 0 |u https://doi.org/10.3390/jpm12101563  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.mdpi.com/2075-4426/12/10/1563  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20221209 
993 |a Article 
994 |a 2022 
998 |g 1074918878  |a Hirche, Christoph  |m 1074918878:Hirche, Christoph  |d 50000  |e 50000PH1074918878  |k 0/50000/  |p 6 
998 |g 123065119  |a Kneser, Ulrich  |m 123065119:Kneser, Ulrich  |d 910000  |d 910400  |d 50000  |e 910000PK123065119  |e 910400PK123065119  |e 50000PK123065119  |k 0/910000/  |k 1/910000/910400/  |k 0/50000/  |p 5 
998 |g 1128238608  |a Diehm, Yannick  |m 1128238608:Diehm, Yannick  |p 4 
999 |a KXP-PPN1826706119  |e 4228701353 
BIB |a Y 
SER |a journal 
JSO |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"eki":["1826706119"],"doi":["10.3390/jpm12101563"]},"physDesc":[{"extent":"16 S."}],"relHost":[{"origin":[{"publisherPlace":"Basel","dateIssuedKey":"2011","dateIssuedDisp":"2011-","publisher":"MDPI"}],"title":[{"subtitle":"open access journal","title_sort":"Journal of Personalized Medicine","title":"Journal of Personalized Medicine"}],"physDesc":[{"extent":"Online-Ressource"}],"part":{"extent":"16","issue":"10","year":"2022","pages":"1-16","text":"12(2022), 10, Artikel-ID 1563, Seite 1-16","volume":"12"},"id":{"zdb":["2662248-8"],"issn":["2075-4426"],"eki":["71862713X"]},"note":["Gesehen am 18.06.20"],"recId":"71862713X","disp":"Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity a 17-year single-center experienceJournal of Personalized Medicine","language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["1.2011 -"]}],"note":["Gesehen am 09.12.2022"],"recId":"1826706119","name":{"displayForm":["Felix Struebing, Lingyun Xiong, Amir K. Bigdeli, Yannick Diehm, Ulrich Kneser, Christoph Hirche and Emre Gazyakan"]},"origin":[{"dateIssuedDisp":"22 September 2022","dateIssuedKey":"2022"}],"person":[{"family":"Strübing","display":"Strübing, Felix","given":"Felix","role":"aut"},{"role":"aut","family":"Xiong","given":"Lingyun","display":"Xiong, Lingyun"},{"role":"aut","given":"Amir K.","display":"Bigdeli, Amir K.","family":"Bigdeli"},{"role":"aut","family":"Diehm","given":"Yannick","display":"Diehm, Yannick"},{"display":"Kneser, Ulrich","given":"Ulrich","family":"Kneser","role":"aut"},{"role":"aut","display":"Hirche, Christoph","given":"Christoph","family":"Hirche"},{"display":"Gazyakan, Emre","given":"Emre","family":"Gazyakan","role":"aut"}],"language":["eng"],"title":[{"subtitle":"a 17-year single-center experience","title_sort":"Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity","title":"Microsurgical strategies after free flap failure in soft tissue reconstruction of the lower extremity"}]} 
SRT |a STRUEBINGFMICROSURGI2220