The prevalence of dry eye in a very old population
Purpose To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a very old population. Methods The Ural Very Old Study (UVOS), a population-based cohort study performed in rural and urban Bashkortostan/Russia, included 1526 (81.1%) out of 1882 eligible individuals...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 April 2022
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| In: |
Acta ophthalmologica
Year: 2022, Jahrgang: 100, Heft: 3, Pages: 262-268 |
| ISSN: | 1755-3768 |
| DOI: | 10.1111/aos.14937 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1111/aos.14937 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14937 
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| Verfasserangaben: | Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Iuliia A. Rusakova, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Songhomitra Panda-Jonas, Timur R. Gilmanshin, Rinat M. Zainullin, Natalia I. Bolshakova, Kamilia R. Safiullina, Ainur V. Gizzatov, Ildar P. Ponomarev, Dilya F. Yakupova, Nail E. Baymukhametov, Nikolay A. Nikitin and Jost B. Jonas |
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| 245 | 1 | 4 | |a The prevalence of dry eye in a very old population |c Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Iuliia A. Rusakova, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Songhomitra Panda-Jonas, Timur R. Gilmanshin, Rinat M. Zainullin, Natalia I. Bolshakova, Kamilia R. Safiullina, Ainur V. Gizzatov, Ildar P. Ponomarev, Dilya F. Yakupova, Nail E. Baymukhametov, Nikolay A. Nikitin and Jost B. Jonas |
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| 264 | 4 | |c 14 June 2021 | |
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| 520 | |a Purpose To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a very old population. Methods The Ural Very Old Study (UVOS), a population-based cohort study performed in rural and urban Bashkortostan/Russia, included 1526 (81.1%) out of 1882 eligible individuals aged 85+ years. The participants underwent a detailed medical and ophthalmological examination including Schirmer´s test, slit-lamp based assessment of the Meibomian glands and an interview. Results The study included 1493 (97.8%) individuals with available information about DED (mean age: 88.3 ± 2.9 years). Schirmer´s test was ≤5 mm in 388 individuals (34.3%; 95% confidence interval (CI): 31.5, 37.1), and the mean score of subjective dry eye symptoms was 7.52 ± 2.14 (median: 6; range: 6-18; 95%CI: 7.41, 7.63). An MGD grade 1, 2, 3 and 4 was diagnosed in 367 (31.4%), 309 (26.4%), 89 (7.6%) and 39 (3.3%) eyes, respectively. The prevalence of DED diagnosis definition #2 (dry eye score ≥8, Schirmer´s test ≤5 mm) and definition #4 (dry eye score ≥7, Schirmer test ≤5 mm, MGD grade 1+), were 164/1132 (14.5%; 95%CI: 12.4, 16.5), and 167/1131 (14.8%; 95%CI: 12.7, 16.8), respectively. In multivariate analysis, higher DED prevalence was associated with female sex (odds ratio (OR): 2.36; 95%CI: 1.18, 4.71; p = 0.02), rural region of habitation (OR: 2.72; 95%CI: 1.10, 6.70; p = 0.03), longer axial length (OR: 1.30; 95%CI: 1.04,1.62; p = 0.02), higher hearing loss score (OR: 1.03; 95%CI: 1.01, 1.05; p = 0.001) and lower self-reported salt consumption (OR: 0.64; 95%CI: 0.54, 0.75; p < 0.001). Conclusions In this population-based recruited very old study sample aged 85+ years, higher DED prevalence (dry eye score ≥8, Schirmer´s test <5 mm; mean: 14.5%) and MGD prevalence (any grade:68.8%) was associated with female sex, rural region of habitation, longer axial length, higher hearing loss score and lower salt consumption. | ||
| 650 | 4 | |a dry eye | |
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a Meibomian gland dysfunction | |
| 650 | 4 | |a Russia | |
| 650 | 4 | |a Ural Very Old Study | |
| 700 | 1 | |a Kazakbaeva, Gyulli M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rakhimova, Ellina M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rusakova, Iuliia A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fakhretdinova, Albina A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tuliakova, Azaliia M. |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Gilmanshin, Timur R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zainullin, Rinat M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bolshakova, Natalia I. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Safiullina, Kamilia R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gizzatov, Ainur V. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ponomarev, Ildar P. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Yakupova, Dilya F. |e VerfasserIn |4 aut | |
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