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The prevalence of dry eye in a very old population

Purpose To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a very old population. Methods The Ural Very Old Study (UVOS), a population-based cohort study performed in rural and urban Bashkortostan/Russia, included 1526 (81.1%) out of 1882 eligible individuals...

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Hauptverfasser: Bikbov, Mukharram (VerfasserIn) , Kazakbaeva, Gyulli M. (VerfasserIn) , Rakhimova, Ellina M. (VerfasserIn) , Rusakova, Iuliia A. (VerfasserIn) , Fakhretdinova, Albina A. (VerfasserIn) , Tuliakova, Azaliia M. (VerfasserIn) , Panda-Jonas, Songhomitra (VerfasserIn) , Gilmanshin, Timur R. (VerfasserIn) , Zainullin, Rinat M. (VerfasserIn) , Bolshakova, Natalia I. (VerfasserIn) , Safiullina, Kamilia R. (VerfasserIn) , Gizzatov, Ainur V. (VerfasserIn) , Ponomarev, Ildar P. (VerfasserIn) , Yakupova, Dilya F. (VerfasserIn) , Baymukhametov, Nail E. (VerfasserIn) , Nikitin, Nikolay A. (VerfasserIn) , Jonas, Jost B. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 April 2022
In: Acta ophthalmologica
Year: 2022, Jahrgang: 100, Heft: 3, Pages: 262-268
ISSN:1755-3768
DOI:10.1111/aos.14937
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/aos.14937
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14937
Volltext
Verfasserangaben:Mukharram M. Bikbov, Gyulli M. Kazakbaeva, Ellina M. Rakhimova, Iuliia A. Rusakova, Albina A. Fakhretdinova, Azaliia M. Tuliakova, Songhomitra Panda-Jonas, Timur R. Gilmanshin, Rinat M. Zainullin, Natalia I. Bolshakova, Kamilia R. Safiullina, Ainur V. Gizzatov, Ildar P. Ponomarev, Dilya F. Yakupova, Nail E. Baymukhametov, Nikolay A. Nikitin and Jost B. Jonas
Beschreibung
Zusammenfassung:Purpose To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a very old population. Methods The Ural Very Old Study (UVOS), a population-based cohort study performed in rural and urban Bashkortostan/Russia, included 1526 (81.1%) out of 1882 eligible individuals aged 85+ years. The participants underwent a detailed medical and ophthalmological examination including Schirmer´s test, slit-lamp based assessment of the Meibomian glands and an interview. Results The study included 1493 (97.8%) individuals with available information about DED (mean age: 88.3 ± 2.9 years). Schirmer´s test was ≤5 mm in 388 individuals (34.3%; 95% confidence interval (CI): 31.5, 37.1), and the mean score of subjective dry eye symptoms was 7.52 ± 2.14 (median: 6; range: 6-18; 95%CI: 7.41, 7.63). An MGD grade 1, 2, 3 and 4 was diagnosed in 367 (31.4%), 309 (26.4%), 89 (7.6%) and 39 (3.3%) eyes, respectively. The prevalence of DED diagnosis definition #2 (dry eye score ≥8, Schirmer´s test ≤5 mm) and definition #4 (dry eye score ≥7, Schirmer test ≤5 mm, MGD grade 1+), were 164/1132 (14.5%; 95%CI: 12.4, 16.5), and 167/1131 (14.8%; 95%CI: 12.7, 16.8), respectively. In multivariate analysis, higher DED prevalence was associated with female sex (odds ratio (OR): 2.36; 95%CI: 1.18, 4.71; p = 0.02), rural region of habitation (OR: 2.72; 95%CI: 1.10, 6.70; p = 0.03), longer axial length (OR: 1.30; 95%CI: 1.04,1.62; p = 0.02), higher hearing loss score (OR: 1.03; 95%CI: 1.01, 1.05; p = 0.001) and lower self-reported salt consumption (OR: 0.64; 95%CI: 0.54, 0.75; p < 0.001). Conclusions In this population-based recruited very old study sample aged 85+ years, higher DED prevalence (dry eye score ≥8, Schirmer´s test <5 mm; mean: 14.5%) and MGD prevalence (any grade:68.8%) was associated with female sex, rural region of habitation, longer axial length, higher hearing loss score and lower salt consumption.
Beschreibung:Gesehen am 14.12.2022
Beschreibung:Online Resource
ISSN:1755-3768
DOI:10.1111/aos.14937

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