Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction
Background - Reperfusion therapy has been shown to improve mortality in patients with acute ST-segment elevation myocardial infarction. However, in randomized clinical trials there was only a modest improvement in left ventricular ejection fraction with reperfusion therapy, despite a larger improvem...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
|
| In: |
International journal of cardiology
Year: 2011, Jahrgang: 146, Heft: 2, Pages: 177-180 |
| ISSN: | 1874-1754 |
| DOI: | 10.1016/j.ijcard.2009.06.034 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ijcard.2009.06.034 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167527309007086 
|
| Verfasserangaben: | Uwe Zeymer, Timm Bauer, Bernard J. Gersh, Ralf Zahn, Anselm Gitt, Claus Jünger, Jochen Senges |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1828643254 | ||
| 003 | DE-627 | ||
| 005 | 20230710095324.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 221222s2011 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ijcard.2009.06.034 |2 doi | |
| 035 | |a (DE-627)1828643254 | ||
| 035 | |a (DE-599)KXP1828643254 | ||
| 035 | |a (OCoLC)1389738524 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Zeymer, Uwe |e VerfasserIn |0 (DE-588)1163486884 |0 (DE-627)1027835694 |0 (DE-576)508027608 |4 aut | |
| 245 | 1 | 0 | |a Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction |c Uwe Zeymer, Timm Bauer, Bernard J. Gersh, Ralf Zahn, Anselm Gitt, Claus Jünger, Jochen Senges |
| 264 | 1 | |c 2011 | |
| 300 | |a 4 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Available online: 14 July 2009 | ||
| 500 | |a Gesehen am 22.12.2022 | ||
| 520 | |a Background - Reperfusion therapy has been shown to improve mortality in patients with acute ST-segment elevation myocardial infarction. However, in randomized clinical trials there was only a modest improvement in left ventricular ejection fraction with reperfusion therapy, despite a larger improvement in mortality. - Methods - In the prospective MITRA-Plus registry we compared 1-year mortality of inhospital survivors of ST-segment elevation myocardial infarction (STEMI) divided into nine groups with preserved (>55%), moderately reduced (41-55%) and severely reduced (≤40%) left ventricular ejection fraction (LVEF) and treated with no early reperfusion therapy, fibrinolysis or primary percutaneous coronary intervention (PCI) within 24h after admission. - Results - A total of 5867 patients were included in this analysis, 1026 (18%) without early reperfusion, 2462 (42%) with fibrinolysis and 2379 (40%) with primary PCI. After adjustment for confounding variables in a propensity score analysis, reperfusion therapy (Odds ratio and 95% CI: 0.27, 0.15-0.48; 0.50, 0.32-0.79; 0.64, 0.44-0.93), fibrinolysis (Odds ratio and 95% CI: 0.27, 0.14-0.52; 0.58, 0.35-0.95; 0.60, 0.39-0.93) and primary PCI (Odds ratio and 95% CI: 0.22, 0.11-0.44; 0.34, 0.19-0.59; 0.56, 0.36-0.88) remained independent predictors of survival in comparison to no reperfusion therapy in the patients with preserved, moderately reduced and severely reduced LVEF, respectively. - Conclusions - These results suggest a beneficial effect of early reperfusion therapy beyond the preservation of left ventricular function, however the mechanisms need further study. | ||
| 650 | 4 | |a Fibrinolysis | |
| 650 | 4 | |a Primary percutaneous coronary intervention | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Reperfusion therapy | |
| 650 | 4 | |a ST-segment elevation myocardial infarction | |
| 700 | 1 | |a Bauer, Timm |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gersh, Bernard J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zahn, Ralf |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gitt, Anselm Kai |d 1964- |e VerfasserIn |0 (DE-588)124753132 |0 (DE-627)365720836 |0 (DE-576)294482792 |4 aut | |
| 700 | 1 | |a Jünger, Claus Heinrich |d 1964- |e VerfasserIn |0 (DE-588)131623346 |0 (DE-627)511708262 |0 (DE-576)298632381 |4 aut | |
| 700 | 1 | |a Senges, Jochen |d 1942- |e VerfasserIn |0 (DE-588)1027133479 |0 (DE-627)728326620 |0 (DE-576)372508685 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of cardiology |d Amsterdam [u.a.] : Elsevier Science, 1981 |g 146(2011), 2, Seite 177-180 |h Online-Ressource |w (DE-627)306659581 |w (DE-600)1500478-8 |w (DE-576)081986270 |x 1874-1754 |7 nnas |a Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction |
| 773 | 1 | 8 | |g volume:146 |g year:2011 |g number:2 |g pages:177-180 |g extent:4 |a Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.ijcard.2009.06.034 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0167527309007086 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20221222 | ||
| 993 | |a Article | ||
| 994 | |a 2011 | ||
| 998 | |g 1027133479 |a Senges, Jochen |m 1027133479:Senges, Jochen |d 50000 |e 50000PS1027133479 |k 0/50000/ |p 7 |y j | ||
| 998 | |g 124753132 |a Gitt, Anselm Kai |m 124753132:Gitt, Anselm Kai |d 50000 |e 50000PG124753132 |k 0/50000/ |p 5 | ||
| 998 | |g 1163486884 |a Zeymer, Uwe |m 1163486884:Zeymer, Uwe |p 1 |x j | ||
| 999 | |a KXP-PPN1828643254 |e 4238430921 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Available online: 14 July 2009","Gesehen am 22.12.2022"],"person":[{"role":"aut","display":"Zeymer, Uwe","family":"Zeymer","given":"Uwe"},{"family":"Bauer","given":"Timm","display":"Bauer, Timm","role":"aut"},{"role":"aut","display":"Gersh, Bernard J.","family":"Gersh","given":"Bernard J."},{"role":"aut","given":"Ralf","family":"Zahn","display":"Zahn, Ralf"},{"given":"Anselm Kai","family":"Gitt","display":"Gitt, Anselm Kai","role":"aut"},{"given":"Claus Heinrich","family":"Jünger","display":"Jünger, Claus Heinrich","role":"aut"},{"role":"aut","given":"Jochen","family":"Senges","display":"Senges, Jochen"}],"title":[{"title":"Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction","title_sort":"Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarction"}],"origin":[{"dateIssuedDisp":"2011","dateIssuedKey":"2011"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"physDesc":[{"extent":"4 S."}],"language":["eng"],"recId":"1828643254","id":{"eki":["1828643254"],"doi":["10.1016/j.ijcard.2009.06.034"]},"name":{"displayForm":["Uwe Zeymer, Timm Bauer, Bernard J. Gersh, Ralf Zahn, Anselm Gitt, Claus Jünger, Jochen Senges"]},"relHost":[{"note":["Gesehen am 13.02.20","Ungezählte Beil.: Supplement"],"title":[{"title_sort":"International journal of cardiology","title":"International journal of cardiology"}],"pubHistory":["1.1981 -"],"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"dateIssuedKey":"1981","dateIssuedDisp":"1981-","publisherPlace":"Amsterdam [u.a.]","publisher":"Elsevier Science"}],"disp":"Beneficial effect of reperfusion therapy beyond the preservation of left ventricular function in patients with acute ST-segment elevation myocardial infarctionInternational journal of cardiology","physDesc":[{"extent":"Online-Ressource"}],"part":{"extent":"4","pages":"177-180","volume":"146","text":"146(2011), 2, Seite 177-180","issue":"2","year":"2011"},"language":["eng"],"recId":"306659581","id":{"eki":["306659581"],"issn":["1874-1754"],"zdb":["1500478-8"]}}]} | ||
| SRT | |a ZEYMERUWEBBENEFICIAL2011 | ||