GLA/DRST real-world outcome analysis of CAR T-cell therapies for large B-cell lymphoma in Germany

CD19-directed chimeric antigen receptor (CAR) T cells have evolved as a new standard-of-care (SOC) treatment in patients with relapsed/refractory (r/r) large B-cell lymphoma (LBCL). Here, we report the first German real-world data on SOC CAR T-cell therapies with the aim to explore risk factors asso...

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Main Authors:	Bethge, Wolfgang Andreas (Author) , Martus, Peter (Author) , Schmitt, Michael (Author) , Holtick, Udo (Author) , Subklewe, Marion (Author) , von Tresckow, Bastian (Author) , Ayuk, Francis (Author) , Wagner-Drouet, Eva Marie (Author) , Wulf, Gerald G. (Author) , Marks, Reinhard (Author) , Penack, Olaf (Author) , Schnetzke, Ulf (Author) , Koenecke, Christian (Author) , von Bonin, Malte (Author) , Stelljes, Matthias (Author) , Glass, Bertram (Author) , Baldus, Claudia D. (Author) , Vucinic, Vladan (Author) , Mougiakakos, Dimitrios (Author) , Topp, Max (Author) , Fante, Matthias A. (Author) , Schroers, Roland (Author) , Bayir, Lale (Author) , Borchmann, Peter (Author) , Buecklein, Veit (Author) , Hasenkamp, Justin (Author) , Hanoun, Christine (Author) , Thomas, Simone (Author) , Beelen, Dietrich W. (Author) , Lengerke, Claudia (Author) , Kroeger, Nicolaus (Author) , Dreger, Peter (Author)
Format:	Article (Journal)
Language:	English
Published:	March 22, 2022
In:	Blood Year: 2022, Volume: 140, Issue: 4, Pages: 349-358
ISSN:	1528-0020
DOI:	10.1182/blood.2021015209
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood.2021015209 Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/140/4/349/484450/GLA-DRST-real-world-outcome-analysis-of-CAR-T-cell
Author Notes:	Wolfgang A. Bethge, Peter Martus, Michael Schmitt, Udo Holtick, Marion Subklewe, Bastian von Tresckow, Francis Ayuk, Eva Marie Wagner-Drouet, Gerald G. Wulf, Reinhard Marks, Olaf Penack, Ulf Schnetzke, Christian Koenecke, Malte von Bonin, Matthias Stelljes, Bertram Glass, Claudia D. Baldus, Vladan Vucinic, Dimitrios Mougiakakos, Max Topp, Matthias A. Fante, Roland Schroers, Lale Bayir, Peter Borchmann, Veit Buecklein, Justin Hasenkamp, Christine Hanoun, Simone Thomas, Dietrich W. Beelen, Claudia Lengerke, Nicolaus Kroeger, and Peter Dreger on behalf of the German Lymphoma Alliance (GLA) and the German Registry for Stem Cell Transplantation (DRST)