Therapeutic reference range for aripiprazole in schizophrenia revised: a systematic review and metaanalysis
While one of the basic axioms of pharmacology postulates that there is a relationship between the concentration and effects of a drug, the value of measuring blood levels is questioned by many clinicians. This is due to the often-missing validation of therapeutic reference ranges.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
05 October 2022
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| In: |
Psychopharmacology
Year: 2022, Jahrgang: 239, Heft: 11, Pages: 3377-3391 |
| ISSN: | 1432-2072 |
| DOI: | 10.1007/s00213-022-06233-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00213-022-06233-2
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| Verfasserangaben: | Xenia M. Hart, Christoph Hiemke, Luzie Eichentopf, Xenija M. Lense, Hans Willi Clement, Andreas Conca, Frank Faltraco, Vincenzo Florio, Jessica Grüner, Ursula Havemann-Reinecke, Espen Molden, Michael Paulzen, Georgios Schoretsanitis, Thomas G. Riemer, Gerhard Gründer |
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| 520 | |a While one of the basic axioms of pharmacology postulates that there is a relationship between the concentration and effects of a drug, the value of measuring blood levels is questioned by many clinicians. This is due to the often-missing validation of therapeutic reference ranges. | ||
| 650 | 4 | |a Adverse drug reaction | |
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| 650 | 4 | |a Dopamine receptor occupancy | |
| 650 | 4 | |a Reference range | |
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