Temporal trends in patients with peripheral artery disease influenced by COVID-19 pandemic

Background: The COVID-19 pandemic influences the health care management of acute and chronic diseases. Data concerning the influence of the pandemic on hospitalizations of patients with peripheral artery disease (PAD) are sparse. Methods: We analysed all patients hospitalized due to PAD between 1 Ja...

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Hauptverfasser: Keller, Karsten (VerfasserIn) , Schmitt, Volker H. (VerfasserIn) , Hobohm, Lukas Martin Alois (VerfasserIn) , Brochhausen, Christoph (VerfasserIn) , Münzel, Thomas (VerfasserIn) , Espinola-Klein, Christine (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 30 October 2022
In: Journal of Clinical Medicine
Year: 2022, Jahrgang: 11, Heft: 21, Pages: 1-13
ISSN:2077-0383
DOI:10.3390/jcm11216433
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/jcm11216433
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2077-0383/11/21/6433
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Verfasserangaben:Karsten Keller, Volker H. Schmitt, Lukas Martin Alois Hobohm, Christoph Brochhausen, Thomas Münzel and Christine Espinola-Klein

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520 |a Background: The COVID-19 pandemic influences the health care management of acute and chronic diseases. Data concerning the influence of the pandemic on hospitalizations of patients with peripheral artery disease (PAD) are sparse. Methods: We analysed all patients hospitalized due to PAD between 1 January 2019 and 31 December 2020 in Germany. Hospitalizations of PAD patients during the pre-pandemic year 2019 were compared to the pandemic year 2020. Results: Overall, 361,029 hospitalizations of PAD patients in the years 2019 and 2020 (55.4% aged ≥70 years; 36.6% females) were included in this study. In the pre-pandemic year of 2019, a total of 25,501 (13.2%) more hospitalizations due to PAD were detected compared to the COVID-19 pandemic year of 2020 (2019: 192,765 [53.4%] vs. 2020: 168,264 [46.6%], p = 0.065). Overall, in 610 (0.4%) of the hospitalization cases, a COVID-19 infection was diagnosed. Regarding interventional/surgical treatments, total numbers of peripheral endovascular intervention of the lower extremity decreased by 9.9% (83,845 vs. 75,519, p < 0.001), surgical peripheral artery revascularization of the lower extremity by 11.4% (32,447 vs. 28,754, p = 0.041) and amputations by 4.0% (20,612 vs. 19,784, p < 0.001) in 2020 compared to 2019. The case fatality rate (2.6% vs. 2.4%, p < 0.001), as well as MACCE rate (3.4% vs. 3.2%, p < 0.001), were slightly higher during the pandemic year 2020 compared to the pre-pandemic year 2019. Conclusions: The COVID-19 pandemic influenced the number of hospitalizations of PAD patients with a 13.2% reduction in hospital admissions and decreased total numbers of revascularization and amputation treatments. 
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