Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma: a series of 12 patients
For patients with advanced basal cell carcinoma (aBCC) first-line treatment with hedgehog inhibitors (HHIs) and second-line treatment with PD1 inhibitors (PD1i) is available, offering combination and sequencing options. Here, we focus on the efficacy and safety of HHI reinduction after PD1i failure.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
7 November 2022
|
| In: |
Cancers
Year: 2022, Jahrgang: 14, Heft: 21, Pages: 1-9 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers14215469 |
| Online-Zugang: | Resolving-System, Volltext: https://doi.org/10.3390/cancers14215469 Verlag, Volltext: https://www.mdpi.com/2072-6694/14/21/5469 |
| Verfasserangaben: | Viola K. DeTemple, Jessica C. Hassel, Michael M. Sachse, Imke Grimmelmann, Ulrike Leiter, Christoffer Gebhardt, Julia Eckardt, Claudia Pföhler, Yenny Angela, Hanna Hübbe and Ralf Gutzmer |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1832496295 | ||
| 003 | DE-627 | ||
| 005 | 20230707000303.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230126s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/cancers14215469 |2 doi | |
| 035 | |a (DE-627)1832496295 | ||
| 035 | |a (DE-599)KXP1832496295 | ||
| 035 | |a (OCoLC)1389536014 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a DeTemple, Viola |d 1992- |e VerfasserIn |0 (DE-588)1156360145 |0 (DE-627)1019153512 |0 (DE-576)502144688 |4 aut | |
| 245 | 1 | 0 | |a Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma |b a series of 12 patients |c Viola K. DeTemple, Jessica C. Hassel, Michael M. Sachse, Imke Grimmelmann, Ulrike Leiter, Christoffer Gebhardt, Julia Eckardt, Claudia Pföhler, Yenny Angela, Hanna Hübbe and Ralf Gutzmer |
| 264 | 1 | |c 7 November 2022 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 26.01.2023 | ||
| 520 | |a For patients with advanced basal cell carcinoma (aBCC) first-line treatment with hedgehog inhibitors (HHIs) and second-line treatment with PD1 inhibitors (PD1i) is available, offering combination and sequencing options. Here, we focus on the efficacy and safety of HHI reinduction after PD1i failure. | ||
| 650 | 4 | |a advanced basal cell carcinoma | |
| 650 | 4 | |a checkpoint inhibition | |
| 650 | 4 | |a hedgehog inhibitor reinduction | |
| 650 | 4 | |a sequential treatment | |
| 700 | 1 | |a Hassel, Jessica C. |d 1975- |e VerfasserIn |0 (DE-588)129790702 |0 (DE-627)480399069 |0 (DE-576)29783715X |4 aut | |
| 700 | 1 | |a Sachse, Michael M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Grimmelmann, Imke |e VerfasserIn |4 aut | |
| 700 | 1 | |a Leiter, Ulrike |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gebhardt, Christoffer |e VerfasserIn |4 aut | |
| 700 | 1 | |a Eckardt, Julia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pföhler, Claudia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Angela, Yenny |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hübbe, Hanna |e VerfasserIn |4 aut | |
| 700 | 1 | |a Gutzmer, Ralf |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cancers |d Basel : MDPI, 2009 |g 14(2022), 21, Artikel-ID 5469, Seite 1-9 |h Online-Ressource |w (DE-627)614095670 |w (DE-600)2527080-1 |w (DE-576)313958548 |x 2072-6694 |7 nnas |a Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma a series of 12 patients |
| 773 | 1 | 8 | |g volume:14 |g year:2022 |g number:21 |g elocationid:5469 |g pages:1-9 |g extent:9 |a Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma a series of 12 patients |
| 856 | 4 | 0 | |u https://doi.org/10.3390/cancers14215469 |x Resolving-System |x Verlag |3 Volltext |
| 856 | 4 | 0 | |u https://www.mdpi.com/2072-6694/14/21/5469 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230126 | ||
| 993 | |a Article | ||
| 994 | |a 2022 | ||
| 998 | |g 129790702 |a Hassel, Jessica C. |m 129790702:Hassel, Jessica C. |d 910000 |d 911300 |d 50000 |e 910000PH129790702 |e 911300PH129790702 |e 50000PH129790702 |k 0/910000/ |k 1/910000/911300/ |k 0/50000/ |p 2 | ||
| 999 | |a KXP-PPN1832496295 |e 4252159296 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1832496295","physDesc":[{"extent":"9 S."}],"relHost":[{"part":{"volume":"14","year":"2022","text":"14(2022), 21, Artikel-ID 5469, Seite 1-9","extent":"9","issue":"21","pages":"1-9"},"id":{"issn":["2072-6694"],"eki":["614095670"],"zdb":["2527080-1"]},"pubHistory":["1.2009 -"],"name":{"displayForm":["Molecular Diversity Preservation International (MDPI)"]},"disp":"Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma a series of 12 patientsCancers","recId":"614095670","physDesc":[{"extent":"Online-Ressource"}],"title":[{"title":"Cancers","title_sort":"Cancers"}],"note":["Gesehen am 27.05.2020"],"type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"origin":[{"publisherPlace":"Basel","dateIssuedKey":"2009","dateIssuedDisp":"2009-","publisher":"MDPI"}]}],"person":[{"display":"DeTemple, Viola","role":"aut","given":"Viola","family":"DeTemple"},{"family":"Hassel","role":"aut","given":"Jessica C.","display":"Hassel, Jessica C."},{"family":"Sachse","given":"Michael M.","role":"aut","display":"Sachse, Michael M."},{"family":"Grimmelmann","role":"aut","given":"Imke","display":"Grimmelmann, Imke"},{"display":"Leiter, Ulrike","given":"Ulrike","role":"aut","family":"Leiter"},{"display":"Gebhardt, Christoffer","family":"Gebhardt","role":"aut","given":"Christoffer"},{"family":"Eckardt","role":"aut","given":"Julia","display":"Eckardt, Julia"},{"display":"Pföhler, Claudia","role":"aut","given":"Claudia","family":"Pföhler"},{"family":"Angela","role":"aut","given":"Yenny","display":"Angela, Yenny"},{"display":"Hübbe, Hanna","role":"aut","given":"Hanna","family":"Hübbe"},{"role":"aut","given":"Ralf","family":"Gutzmer","display":"Gutzmer, Ralf"}],"origin":[{"dateIssuedDisp":"7 November 2022","dateIssuedKey":"2022"}],"title":[{"title_sort":"Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma","title":"Reinduction of hedgehog inhibitors after checkpoint inhibition in advanced basal cell carcinoma","subtitle":"a series of 12 patients"}],"note":["Gesehen am 26.01.2023"],"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"name":{"displayForm":["Viola K. DeTemple, Jessica C. Hassel, Michael M. Sachse, Imke Grimmelmann, Ulrike Leiter, Christoffer Gebhardt, Julia Eckardt, Claudia Pföhler, Yenny Angela, Hanna Hübbe and Ralf Gutzmer"]},"id":{"eki":["1832496295"],"doi":["10.3390/cancers14215469"]}} | ||
| SRT | |a DETEMPLEVIREINDUCTIO7202 | ||