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Low levels of Methyl-CpG binding protein 2 are accompanied by an increased vulnerability to the negative outcomes of stress exposure during childhood in healthy women

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Numerous mental illnesses arise following stressful events in vulnerable individuals, with females being generally more affected than males. Adverse childhood experiences are known to increase the risk of developing psychopathologies and DNA methylation was demonstrated to drive the long-lasting eff...

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Main Authors: Cosentino, Livia (Author) , Zidda, Francesca (Author) , Dukal, Helene (Author) , Witt, Stephanie (Author) , De Filippis, Bianca (Author) , Flor, Herta (Author)
Format: Article (Journal)
Language:English
Published: 08 December 2022
In: Translational Psychiatry
Year: 2022, Volume: 12, Pages: 1-8
ISSN:2158-3188
DOI:10.1038/s41398-022-02259-4
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1038/s41398-022-02259-4
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41398-022-02259-4
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Author Notes:Livia Cosentino, Francesca Zidda, Helene Dukal, Stephanie H. Witt, Bianca De Filippis and Herta Flor
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Methyl-CpG binding protein 2 functional alterations provide vulnerability to develop behavioral and molecular features of post-traumatic stress disorder in male mice by Cosentino, Livia (Author) , Vigli, Daniele (Author) , Medici, Vanessa (Author) , Flor, Herta (Author) , Lucarelli, Marco (Author) , Fuso, Andrea (Author) , De Filippis, Bianca (Author) ,


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