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LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence

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Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF), which controls fundamental biological processes such as cell growth, migration, and differentiation. MRTF and SRF transcriptional activity play an important role in hepatocellular carcinoma (HCC)...

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Main Authors: Konopa, Andreas (Author) , Meier, Melanie A. (Author) , Franz, Miriam J. (Author) , Bernardinelli, Emanuele (Author) , Voegele, Anna-Lena (Author) , Atreya, Raja (Author) , Ribback, Silvia (Author) , Rössler, Stephanie (Author) , Aigner, Achim (Author) , Singer, Kerstin (Author) , Singer, Stephan (Author) , Sarikas, Antonio (Author) , Muehlich, Susanne (Author)
Format: Article (Journal)
Language:English
Published: 28 December 2022
In: Oncogenesis
Year: 2022, Volume: 11, Pages: 1-12
ISSN:2157-9024
DOI:10.1038/s41389-022-00445-z
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41389-022-00445-z
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41389-022-00445-z
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Author Notes:Andreas Konopa, Melanie A. Meier, Miriam J. Franz, Emanuele Bernardinelli, Anna-Lena Voegele, Raja Atreya, Silvia Ribback, Stephanie Roessler, Achim Aigner, Kerstin Singer, Stephan Singer, Antonio Sarikas and Susanne Muehlich
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Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel ROS1 fusion gene and PBX1 as prognostic marker by Plum, Patrick Sven (Author) , Hess, Timo (Author) , Bertrand, Denis (Author) , Morgenstern, Isabelle (Author) , Velazquez Camacho, Oscar (Author) , Jonas, Christoph (Author) , Alidousty, Christina (Author) , Wagner, Britta (Author) , Rössler, Stephanie (Author) , Albrecht, Thomas (Author) , Becker, Jessica (Author) , Richartz, Vanessa (Author) , Holz, Barbara (Author) , Hoppe, Sascha (Author) , Poh, Huay Mei (Author) , Chia, Burton Kuan Hui (Author) , Chan, Cheryl Xueli (Author) , Pathiraja, Thushangi (Author) , Teo, Audrey SM (Author) , Marquardt, Jens U. (Author) , Khng, Alexis (Author) , Heise, Michael (Author) , Fei, Yao (Author) , Thieme, René (Author) , Klein, Sebastian (Author) , Hong, Jing Han (Author) , Dima, Simona O (Author) , Popescu, Irinel (Author) , Hoppe-Lotichius, Maria (Author) , Buettner, Reinhard (Author) , Lautem, Anja (Author) , Otto, Gerd (Author) , Quaas, Alexander (Author) , Nagarajan, Niranjan (Author) , Rozen, Steve (Author) , Teh, Bin Tean (Author) , Goeppert, Benjamin (Author) , Drebber, Uta (Author) , Lang, Hauke (Author) , Tan, Patrick (Author) , Gockel, Ines (Author) , Schumacher, Johannes (Author) , Hillmer, Axel M. (Author) ,


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Programmed Death Ligand-1 (PD-L1) is an independent negative prognosticator in Western-world gallbladder cancer by Albrecht, Thomas (Author) , Brinkmann, Fritz (Author) , Albrecht, Michael (Author) , Lonsdorf, Anke Susanne (Author) , Mehrabi, Arianeb (Author) , Hoffmann, Katrin (Author) , Kulu, Yakup (Author) , Charbel, Alphonse (Author) , Vogel, Monika Nadja (Author) , Rupp, Christian (Author) , Köhler, Bruno Christian (Author) , Springfeld, Christoph (Author) , Schirmacher, Peter (Author) , Rössler, Stephanie (Author) , Goeppert, Benjamin (Author) ,


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