Drug-coated balloons in below-the-knee arteries: analysis of a real-world data set
Summary:Background: The search for an optimal interventional treatment strategy in infrapopliteal peripheral artery disease remains in the focus of interest. Whether drug-coated balloons (DCB) might enhance interventional outcomes after crural interventions is a matter of debate, as studies yielded...
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
May 23, 2022
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| In: |
Vasa
Year: 2022, Volume: 51, Issue: 4, Pages: 256-262 |
| ISSN: | 1664-2872 |
| DOI: | 10.1024/0301-1526/a001009 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1024/0301-1526/a001009 Verlag, lizenzpflichtig, Volltext: https://econtent.hogrefe.com/doi/10.1024/0301-1526/a001009 
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| Author Notes: | Felicitas Stoll, Reyhan Uslu, Erwin Blessing, Norbert Frey, Hugo A. Katus, Christian Erbel, Britta Heilmeier and Oliver J. Müller |
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| 245 | 1 | 0 | |a Drug-coated balloons in below-the-knee arteries |b analysis of a real-world data set |c Felicitas Stoll, Reyhan Uslu, Erwin Blessing, Norbert Frey, Hugo A. Katus, Christian Erbel, Britta Heilmeier and Oliver J. Müller |
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| 520 | |a Summary:Background: The search for an optimal interventional treatment strategy in infrapopliteal peripheral artery disease remains in the focus of interest. Whether drug-coated balloons (DCB) might enhance interventional outcomes after crural interventions is a matter of debate, as studies yielded conflicting results on DCB safety and efficacy. Patients and methods: We analyzed a retrospective cohort of 75 infrapopliteal DCB interventions performed at our institution in 68 patients with peripheral artery disease in Rutherford category 3 to 6. Results: Despite a high rate of long complex lesions and multi-vessel disease, freedom from clinically driven target lesions revascularization (TLR) after 365 days was 68%. After six months, healing or significant improvement of the ischemic ulcer was observed in 78% of cases. Accordingly, freedom from major amputation and death after 365 days was 82%. Freedom from major amputation and death was 76.2% of cases in patients with diabetes mellitus as opposed to 91.5% in patients without diabetes mellitus (p=0.049). Conclusions: With this real-world analysis we would like to contribute to the ongoing discussion on the benefit and safety of DCB treatment in below-the-knee interventions. | ||
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