Buchumschlag

Drug-coated balloons in below-the-knee arteries: analysis of a real-world data set

Summary:Background: The search for an optimal interventional treatment strategy in infrapopliteal peripheral artery disease remains in the focus of interest. Whether drug-coated balloons (DCB) might enhance interventional outcomes after crural interventions is a matter of debate, as studies yielded...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Stoll, Felicitas E. (VerfasserIn) , Uslu, Reyhan (VerfasserIn) , Blessing, Erwin (VerfasserIn) , Frey, Norbert (VerfasserIn) , Katus, Hugo (VerfasserIn) , Erbel, Christian (VerfasserIn) , Heilmeier, Britta (VerfasserIn) , Müller, Oliver J. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: May 23, 2022
In: Vasa
Year: 2022, Jahrgang: 51, Heft: 4, Pages: 256-262
ISSN:1664-2872
DOI:10.1024/0301-1526/a001009
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1024/0301-1526/a001009
Verlag, lizenzpflichtig, Volltext: https://econtent.hogrefe.com/doi/10.1024/0301-1526/a001009
Volltext
Verfasserangaben:Felicitas Stoll, Reyhan Uslu, Erwin Blessing, Norbert Frey, Hugo A. Katus, Christian Erbel, Britta Heilmeier and Oliver J. Müller
Beschreibung
Zusammenfassung:Summary:Background: The search for an optimal interventional treatment strategy in infrapopliteal peripheral artery disease remains in the focus of interest. Whether drug-coated balloons (DCB) might enhance interventional outcomes after crural interventions is a matter of debate, as studies yielded conflicting results on DCB safety and efficacy. Patients and methods: We analyzed a retrospective cohort of 75 infrapopliteal DCB interventions performed at our institution in 68 patients with peripheral artery disease in Rutherford category 3 to 6. Results: Despite a high rate of long complex lesions and multi-vessel disease, freedom from clinically driven target lesions revascularization (TLR) after 365 days was 68%. After six months, healing or significant improvement of the ischemic ulcer was observed in 78% of cases. Accordingly, freedom from major amputation and death after 365 days was 82%. Freedom from major amputation and death was 76.2% of cases in patients with diabetes mellitus as opposed to 91.5% in patients without diabetes mellitus (p=0.049). Conclusions: With this real-world analysis we would like to contribute to the ongoing discussion on the benefit and safety of DCB treatment in below-the-knee interventions.
Beschreibung:Gesehen am 27.02.2023
Beschreibung:Online Resource
ISSN:1664-2872
DOI:10.1024/0301-1526/a001009

Ähnliche Einträge