Synergistic effect of cinacalcet and active vitamin D in a dialysis patient with secondary hyperparathyroidism
While treating a long-term dialysis patient for secondary hyperparathyroidism (SHPT), indications of a synergistic effect between cinacalcet HCl and active vitamin D were observed. After 2.5 years, high initial cinacalcet doses of 180 mg/day could be significantly reduced to only 30 mg/non-dialysis...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
25 February 2010
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| In: |
Dialysis & transplantation
Year: 2010, Volume: 39, Issue: 2, Pages: 69-71 |
| ISSN: | 1932-6920 |
| DOI: | 10.1002/dat.20405 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/dat.20405 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/dat.20405 
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| Author Notes: | Christian P. Karger, Vedat Schwenger, Claudia Sommerer, Martin Zeier |
| Summary: | While treating a long-term dialysis patient for secondary hyperparathyroidism (SHPT), indications of a synergistic effect between cinacalcet HCl and active vitamin D were observed. After 2.5 years, high initial cinacalcet doses of 180 mg/day could be significantly reduced to only 30 mg/non-dialysis day without losing control over the intact parathyroid hormone. Calcium-phosphorus product improved over time. The combination of cinacalcet and active vitamin D may improve the treatment of SHPT in dialysis patients. |
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| Item Description: | Gesehen am 02.03.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1932-6920 |
| DOI: | 10.1002/dat.20405 |