Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer
Antitumor inflammatory response is known to inhibit tumor growth in colorectal carcinoma. The density and functionality of tumor-infiltrating lymphocytes (TIL) is regulated by the antigen processing machinery through regulator proteins such as transporters associated with antigen processing (TAP) an...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 September 2010
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| In: |
Human pathology
Year: 2010, Jahrgang: 41, Heft: 12, Pages: 1758-1769 |
| ISSN: | 1532-8392 |
| DOI: | 10.1016/j.humpath.2010.05.014 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.humpath.2010.05.014 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0046817710002054 
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| Verfasserangaben: | Atsuko Kasajima, Christine Sers, Hironobu Sasano, Korinna Jöhrens, Albrecht Stenzinger, Aurelia Noske, Ann-Christin Buckendahl, Silvia Darb-Esfahani, Berit Maria Müller, Jan Budczies, Annika Lehman, Manfred Dietel, Carsten Denkert, Wilko Weichert |
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| 520 | |a Antitumor inflammatory response is known to inhibit tumor growth in colorectal carcinoma. The density and functionality of tumor-infiltrating lymphocytes (TIL) is regulated by the antigen processing machinery through regulator proteins such as transporters associated with antigen processing (TAP) and major histocompatibility complex (MHC) class I antigen. We aimed to investigate the in vivo association of those factors and their impact on prognosis in colorectal cancer. | ||
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| 650 | 4 | |a Inflammation | |
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