Microcystic adnexal carcinoma: aggressive infiltrative tumor often with innocent clinical appearance
Microcystic adnexal carcinoma is a rare sweat gland malignancy, characterized by slow, but aggressive infiltrative growth. Histologic characteristics are follicular and glandular differentiation, as well as bland cytologic features. The benign histologic appearance, particularly in the upper level o...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
[April 2010]
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| In: |
Journal der Deutschen Dermatologischen Gesellschaft
Year: 2010, Volume: 8, Issue: 4, Pages: 275-278 |
| ISSN: | 1610-0387 |
| DOI: | 10.1111/j.1610-0387.2009.07254.x |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1610-0387.2009.07254.x Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1610-0387.2009.07254.x 
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| Author Notes: | Corinna Hamsch, Wolfgang Hartschuh (Department of Dermatology, University Hospital Heidelberg, Germany) |
| Summary: | Microcystic adnexal carcinoma is a rare sweat gland malignancy, characterized by slow, but aggressive infiltrative growth. Histologic characteristics are follicular and glandular differentiation, as well as bland cytologic features. The benign histologic appearance, particularly in the upper level of the tumor, can be confused with syringoma or benign follicular neoplasm. Thus the risk of misdiagnosis is considerable, especially if only superficial biopsies are provided. We report two patients with microcystic adnexal carcinoma, using them as a basis to discuss, pathogenesis, diagnosis, histology and therapy of the tumor. |
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| Item Description: | First published: 25 March 2010 Gesehen am 08.03.2023 |
| Physical Description: | Online Resource |
| ISSN: | 1610-0387 |
| DOI: | 10.1111/j.1610-0387.2009.07254.x |