Microcystic adnexal carcinoma: aggressive infiltrative tumor often with innocent clinical appearance

Microcystic adnexal carcinoma is a rare sweat gland malignancy, characterized by slow, but aggressive infiltrative growth. Histologic characteristics are follicular and glandular differentiation, as well as bland cytologic features. The benign histologic appearance, particularly in the upper level o...

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Hauptverfasser: Hamsch, Corinna (VerfasserIn) , Hartschuh, Wolfgang (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: [April 2010]
In: Journal der Deutschen Dermatologischen Gesellschaft
Year: 2010, Jahrgang: 8, Heft: 4, Pages: 275-278
ISSN:1610-0387
DOI:10.1111/j.1610-0387.2009.07254.x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1610-0387.2009.07254.x
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1610-0387.2009.07254.x
Volltext
Verfasserangaben:Corinna Hamsch, Wolfgang Hartschuh (Department of Dermatology, University Hospital Heidelberg, Germany)
Beschreibung
Zusammenfassung:Microcystic adnexal carcinoma is a rare sweat gland malignancy, characterized by slow, but aggressive infiltrative growth. Histologic characteristics are follicular and glandular differentiation, as well as bland cytologic features. The benign histologic appearance, particularly in the upper level of the tumor, can be confused with syringoma or benign follicular neoplasm. Thus the risk of misdiagnosis is considerable, especially if only superficial biopsies are provided. We report two patients with microcystic adnexal carcinoma, using them as a basis to discuss, pathogenesis, diagnosis, histology and therapy of the tumor.
Beschreibung:First published: 25 March 2010
Gesehen am 08.03.2023
Beschreibung:Online Resource
ISSN:1610-0387
DOI:10.1111/j.1610-0387.2009.07254.x