A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning probe microscopy

Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in principle enables one to obtain three dimensional data, the reconstruction of cell volume from z-stacks is a time consuming procedure....

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Hauptverfasser: Happel, Patrick (VerfasserIn) , Möller, Kerstin (VerfasserIn) , Kunz, Ralf (VerfasserIn) , Dietzel, Irmgard D. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 15 June 2010
In: BMC bioinformatics
Year: 2010, Jahrgang: 11, Pages: 1-16
ISSN:1471-2105
DOI:10.1186/1471-2105-11-323
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2105-11-323
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Verfasserangaben:Patrick Happel, Kerstin Möller, Ralf Kunz and Irmgard D. Dietzel
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Zusammenfassung:Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in principle enables one to obtain three dimensional data, the reconstruction of cell volume from z-stacks is a time consuming procedure. Thus, three dimensional topographic representations of cells are easier to obtain by scanning probe microscopical measurements.
Beschreibung:Gesehen am 08.03.2023
Beschreibung:Online Resource
ISSN:1471-2105
DOI:10.1186/1471-2105-11-323