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DanTox: a novel joint research project using zebrafish (Danio rerio) to identify specific toxicity and molecular modes of action of sediment-bound pollutants

The European Water Framework Directive aims to achieve a good ecological and chemical status in surface water of European rivers by the year 2015. Since sediments and particulate matter act as secondary sources for pollutants, applied sediment toxicology is perceived to play a major role for obtaini...

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Main Authors: Keiter, Steffen (Author) , Peddinghaus, Sabrina (Author) , Feiler, Ute (Author) , Kais, Britta (Author) , Hafner, Christoph (Author) , Ho, Nga Yu (Author) , Rastegar, Sepand (Author) , Otte, Jens C. (Author) , Ottermanns, Richard (Author) , Reifferscheid, Georg (Author) , Strähle, Uwe (Author) , Braunbeck, Thomas (Author) , Hammers-Wirtz, Monika (Author) , Hollert, Henner (Author)
Format: Article (Journal)
Language:English
Published: 14 April 2010
In: Journal of soils and sediments
Year: 2010, Volume: 10, Issue: 4, Pages: 714-717
ISSN:1614-7480
DOI:10.1007/s11368-010-0221-7
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11368-010-0221-7
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s11368-010-0221-7
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Author Notes:Steffen Keiter, Sabrina Peddinghaus, Ute Feiler, Britta von der Goltz, Christoph Hafner, Nga Yu Ho, Sepand Rastegar, Jens C. Otte, Richard Ottermanns, Georg Reifferscheid, Uwe Strähle, Thomas Braunbeck, Monika Hammers-Wirtz, Henner Hollert
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Summary:The European Water Framework Directive aims to achieve a good ecological and chemical status in surface water of European rivers by the year 2015. Since sediments and particulate matter act as secondary sources for pollutants, applied sediment toxicology is perceived to play a major role for obtaining new knowledge that can contribute to successful attainment of the goal. However, the existing bioassays for sediment toxicity analyses do not provide sufficient data concerning bioavailability of environmental pollutants. In this regard, there is an urgent need to combine sediment contact assays with gene expression analysis to investigate mechanism-specific sediment toxicity.
Item Description:Gesehen am 08.03.2023
Physical Description:Online Resource
ISSN:1614-7480
DOI:10.1007/s11368-010-0221-7

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