Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation

With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need for more accurate drug dosing has become evident. Personalized immunosuppressive therapy requires better strategies for avoidance of drug-related toxicity while maintaining efficacy. Few studies have assessed...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kuypers, Dirk (VerfasserIn) , Meur, Yannick Le (VerfasserIn) , Cantarovich, Marcelo (VerfasserIn) , Tredger, Michael J. (VerfasserIn) , Tett, Susan E. (VerfasserIn) , Cattaneo, Dario (VerfasserIn) , Tönshoff, Burkhard (VerfasserIn) , Holt, David W. (VerfasserIn) , Chapman, Jeremy (VerfasserIn) , Gelder, Teun van (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: February 2010
In: Clinical journal of the American Society of Nephrology
Year: 2010, Jahrgang: 5, Heft: 2, Pages: 341-358
ISSN:1555-905X
DOI:10.2215/CJN.07111009
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2215/CJN.07111009
Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=2010&issue=02000&article=00030&type=Fulltext
Volltext
Verfasserangaben:Dirk R.J. Kuypers, Yannick Le Meur, Marcelo Cantarovich, Michael J. Tredger, Susan E. Tett, Dario Cattaneo, Burkhard Tönshoff, David W. Holt, Jeremy Chapman, Teun van Gelder, for The Transplantation Society (TTS) Consensus Group on TDM of Mpa

MARC

LEADER 00000caa a2200000 c 4500
001 1838723633
003 DE-627
005 20230710152952.0
007 cr uuu---uuuuu
008 230309s2010 xx |||||o 00| ||eng c
024 7 |a 10.2215/CJN.07111009  |2 doi 
035 |a (DE-627)1838723633 
035 |a (DE-599)KXP1838723633 
035 |a (OCoLC)1389821069 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Kuypers, Dirk  |e VerfasserIn  |0 (DE-588)1282901478  |0 (DE-627)1838725458  |4 aut 
245 1 0 |a Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation  |c Dirk R.J. Kuypers, Yannick Le Meur, Marcelo Cantarovich, Michael J. Tredger, Susan E. Tett, Dario Cattaneo, Burkhard Tönshoff, David W. Holt, Jeremy Chapman, Teun van Gelder, for The Transplantation Society (TTS) Consensus Group on TDM of Mpa 
264 1 |c February 2010 
300 |a 18 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 09.03.2023 
500 |a DOI funktioniert nicht 
520 |a With the increasing use of mycophenolic acid (MPA) in solid organ transplantation, the need for more accurate drug dosing has become evident. Personalized immunosuppressive therapy requires better strategies for avoidance of drug-related toxicity while maintaining efficacy. Few studies have assessed the clinical usefulness of therapeutic drug monitoring (TDM) of MPA in solid organ transplantation in a prospective way, and they have produced opposing results. To provide clinicians with an objective and balanced clinical interpretation of the current scientific evidence on TDM of MPA, a consensus meeting involving 47 experts from around the world was commissioned by The Transplantation Society and held in Rome on November 20 to 21, 2008. The goal of this consensus meeting was to offer information to transplant practitioners on clinically relevant pharmacokinetic characteristics of MPA, to rationalize the basis for currently advised target exposure ranges for MPA in various types of organ transplantation, and to summarize available methods for application of MPA TDM in clinical practice. Although this consensus report does not evaluate the final role of MPA TDM in transplantation, it seeks to examine the current scientific evidence for concentration-controlled dosing of MPA. 
700 1 |a Meur, Yannick Le  |e VerfasserIn  |4 aut 
700 1 |a Cantarovich, Marcelo  |e VerfasserIn  |4 aut 
700 1 |a Tredger, Michael J.  |e VerfasserIn  |4 aut 
700 1 |a Tett, Susan E.  |e VerfasserIn  |4 aut 
700 1 |a Cattaneo, Dario  |e VerfasserIn  |4 aut 
700 1 |a Tönshoff, Burkhard  |e VerfasserIn  |0 (DE-588)1032445823  |0 (DE-627)738463493  |0 (DE-576)173494196  |4 aut 
700 1 |a Holt, David W.  |e VerfasserIn  |4 aut 
700 1 |a Chapman, Jeremy  |e VerfasserIn  |4 aut 
700 1 |a Gelder, Teun van  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |a American Society of Nephrology  |t Clinical journal of the American Society of Nephrology  |d Washington, DC : American Society of Nephrology, 2006  |g 5(2010), 2 vom: Feb., Seite 341-358  |h Online-Ressource  |w (DE-627)50595091X  |w (DE-600)2216582-4  |w (DE-576)30683281X  |x 1555-905X  |7 nnas 
773 1 8 |g volume:5  |g year:2010  |g number:2  |g month:02  |g pages:341-358  |g extent:18  |a Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation 
856 4 0 |u https://doi.org/10.2215/CJN.07111009  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://journals.lww.com/cjasn/pages/articleviewer.aspx?year=2010&issue=02000&article=00030&type=Fulltext  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20230309 
993 |a Article 
994 |a 2010 
998 |g 1032445823  |a Tönshoff, Burkhard  |m 1032445823:Tönshoff, Burkhard  |d 910000  |d 910500  |d 50000  |e 910000PT1032445823  |e 910500PT1032445823  |e 50000PT1032445823  |k 0/910000/  |k 1/910000/910500/  |k 0/50000/  |p 7 
999 |a KXP-PPN1838723633  |e 4285751569 
BIB |a Y 
SER |a journal 
JSO |a {"recId":"1838723633","language":["eng"],"note":["Gesehen am 09.03.2023","DOI funktioniert nicht"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation","title_sort":"Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation"}],"person":[{"display":"Kuypers, Dirk","roleDisplay":"VerfasserIn","role":"aut","family":"Kuypers","given":"Dirk"},{"family":"Meur","given":"Yannick Le","display":"Meur, Yannick Le","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Cantarovich, Marcelo","role":"aut","family":"Cantarovich","given":"Marcelo"},{"family":"Tredger","given":"Michael J.","roleDisplay":"VerfasserIn","display":"Tredger, Michael J.","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Tett, Susan E.","given":"Susan E.","family":"Tett"},{"family":"Cattaneo","given":"Dario","roleDisplay":"VerfasserIn","display":"Cattaneo, Dario","role":"aut"},{"display":"Tönshoff, Burkhard","roleDisplay":"VerfasserIn","role":"aut","family":"Tönshoff","given":"Burkhard"},{"given":"David W.","family":"Holt","role":"aut","roleDisplay":"VerfasserIn","display":"Holt, David W."},{"display":"Chapman, Jeremy","roleDisplay":"VerfasserIn","role":"aut","family":"Chapman","given":"Jeremy"},{"role":"aut","display":"Gelder, Teun van","roleDisplay":"VerfasserIn","given":"Teun van","family":"Gelder"}],"relHost":[{"titleAlt":[{"title":"CJASN"}],"part":{"extent":"18","text":"5(2010), 2 vom: Feb., Seite 341-358","volume":"5","issue":"2","pages":"341-358","year":"2010"},"pubHistory":["1.2006 -"],"corporate":[{"role":"aut","display":"American Society of Nephrology","roleDisplay":"VerfasserIn"}],"language":["eng"],"recId":"50595091X","type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"American Society of NephrologyClinical journal of the American Society of Nephrology","note":["Gesehen am 04.08.2025"],"title":[{"title_sort":"Clinical journal of the American Society of Nephrology","title":"Clinical journal of the American Society of Nephrology","subtitle":"CJASN"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1555-905X"],"eki":["50595091X"],"zdb":["2216582-4"]},"origin":[{"dateIssuedDisp":"2006-","dateIssuedKey":"2006","publisher":"American Society of Nephrology","publisherPlace":"Washington, DC"}]}],"physDesc":[{"extent":"18 S."}],"id":{"doi":["10.2215/CJN.07111009"],"eki":["1838723633"]},"origin":[{"dateIssuedKey":"2010","dateIssuedDisp":"February 2010"}],"name":{"displayForm":["Dirk R.J. Kuypers, Yannick Le Meur, Marcelo Cantarovich, Michael J. Tredger, Susan E. Tett, Dario Cattaneo, Burkhard Tönshoff, David W. Holt, Jeremy Chapman, Teun van Gelder, for The Transplantation Society (TTS) Consensus Group on TDM of Mpa"]}} 
SRT |a KUYPERSDIRCONSENSUSR2010