The IGF/IGFBP system in relation to macroscopic bone architecture in pediatric renal transplant patients
The post-transplant bone disease of the peripheral skeleton in pediatric renal transplant recipients is characterized by an inadequately thin bone cortex in relation to muscular force. A major hormonal modulator of periosteal growth is the insulin-like growth factor (IGF)/IGF binding protein (IGFBP)...
Gespeichert in:
| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2010
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| In: |
Pediatric nephrology
Year: 2010, Jahrgang: 25, Heft: 4, Pages: 659-667 |
| ISSN: | 1432-198X |
| DOI: | 10.1007/s00467-009-1405-5 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00467-009-1405-5 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00467-009-1405-5 |
| Verfasserangaben: | Daniela Kiepe, Eva-Maria Rüth, Werner F. Blum, Subburaman Mohan, Lutz T. Weber, Burkhard Tönshoff |
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| 520 | |a The post-transplant bone disease of the peripheral skeleton in pediatric renal transplant recipients is characterized by an inadequately thin bone cortex in relation to muscular force. A major hormonal modulator of periosteal growth is the insulin-like growth factor (IGF)/IGF binding protein (IGFBP) system. We therefore hypothesized that the reduced cortical thickness in these patients may be due to functional IGF deficiency. | ||
| 650 | 4 | |a IGF/IGFBP system | |
| 650 | 4 | |a Pediatric renal transplant recipients | |
| 650 | 4 | |a Peripheral quantitative computed tomography | |
| 650 | 4 | |a Post-transplant bone disease | |
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