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Bronchoalveolar lavage immunodiagnosis for tuberculosis suspects in Europe and Africa

We read with interest the article by Dheda et al 1 who followed our approach for a rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage (BAL) enzyme-linked immunospot (ELISpot)2 in a country of high tuberculosis incidence, including individuals with HIV-1 infection. - - The auth...

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Main Authors: Lange, Christoph (Author) , Bossink, Aik (Author) , Eberhardt, Ralf (Author) , Goletti, Delia (Author) , Jafari, Claudia (Author) , Latorre, Irene (Author) , Kirsten, Detlef (Author) , Losi, Monica (Author) , Migliori, Giovanni B. (Author) , Sotgiu, Giovanni (Author)
Format: Article (Journal) Editorial
Language:English
Published: August 30, 2010
In: Thorax
Year: 2010, Volume: 65, Issue: 9, Pages: 842
ISSN:1468-3296
DOI:10.1136/thx.2009.124958
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/thx.2009.124958
Verlag, lizenzpflichtig, Volltext: https://thorax.bmj.com/content/65/9/842.1
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Author Notes:Christoph Lange, Aik Bossink, Ralf Eberhardt, Delia Goletti, Claudia Jafari, Irene Latorre, Detlef Kirsten, Monica Losi, Giovanni B. Migliori, Giovanni Sotgiu
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Summary:We read with interest the article by Dheda et al 1 who followed our approach for a rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage (BAL) enzyme-linked immunospot (ELISpot)2 in a country of high tuberculosis incidence, including individuals with HIV-1 infection. - - The authors report a sensitivity of 88.9% and specificity of 94.7% of the BAL ELISpot (T-SPOT.TB test) for the diagnosis of tuberculosis in suspects with scarce or negative acid-fast bacilli (AFB) sputum smears. This observation is important, as it confirms the findings of other …
Item Description:Gesehen am 09.03.2023
Physical Description:Online Resource
ISSN:1468-3296
DOI:10.1136/thx.2009.124958

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