Bronchoalveolar lavage immunodiagnosis for tuberculosis suspects in Europe and Africa

We read with interest the article by Dheda et al 1 who followed our approach for a rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage (BAL) enzyme-linked immunospot (ELISpot)2 in a country of high tuberculosis incidence, including individuals with HIV-1 infection. - - The auth...

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Hauptverfasser: Lange, Christoph (VerfasserIn) , Bossink, Aik (VerfasserIn) , Eberhardt, Ralf (VerfasserIn) , Goletti, Delia (VerfasserIn) , Jafari, Claudia (VerfasserIn) , Latorre, Irene (VerfasserIn) , Kirsten, Detlef (VerfasserIn) , Losi, Monica (VerfasserIn) , Migliori, Giovanni B. (VerfasserIn) , Sotgiu, Giovanni (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: August 30, 2010
In: Thorax
Year: 2010, Jahrgang: 65, Heft: 9, Pages: 842
ISSN:1468-3296
DOI:10.1136/thx.2009.124958
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/thx.2009.124958
Verlag, lizenzpflichtig, Volltext: https://thorax.bmj.com/content/65/9/842.1
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Verfasserangaben:Christoph Lange, Aik Bossink, Ralf Eberhardt, Delia Goletti, Claudia Jafari, Irene Latorre, Detlef Kirsten, Monica Losi, Giovanni B. Migliori, Giovanni Sotgiu
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Zusammenfassung:We read with interest the article by Dheda et al 1 who followed our approach for a rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage (BAL) enzyme-linked immunospot (ELISpot)2 in a country of high tuberculosis incidence, including individuals with HIV-1 infection. - - The authors report a sensitivity of 88.9% and specificity of 94.7% of the BAL ELISpot (T-SPOT.TB test) for the diagnosis of tuberculosis in suspects with scarce or negative acid-fast bacilli (AFB) sputum smears. This observation is important, as it confirms the findings of other …
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Beschreibung:Online Resource
ISSN:1468-3296
DOI:10.1136/thx.2009.124958