Imaging phenotypes of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide. COPD is defined by irreversible airflow obstruction. It is a heterogeneous disease affecting the airways and/or the parenchyma with different severity during the course of the disease. The...

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Hauptverfasser: Ley-Zaporozhan, Julia (VerfasserIn) , Beek, Edwin J.R. van (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 23 November 2010
In: Journal of magnetic resonance imaging
Year: 2010, Jahrgang: 32, Heft: 6, Pages: 1340-1352
ISSN:1522-2586
DOI:10.1002/jmri.22376
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/jmri.22376
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.22376
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Verfasserangaben:Julia Ley-Zaporozhan and Edwin J.R. van Beek

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520 |a Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide. COPD is defined by irreversible airflow obstruction. It is a heterogeneous disease affecting the airways and/or the parenchyma with different severity during the course of the disease. These different aspects of COPD can be addressed by imaging using a combination of morphological and functional techniques. Computed tomography (CT) is the technique of choice for morphological imaging of the lung parenchyma and airways. This morphological information is to be accomplished by functional information about ventilation and perfusion, mainly provided by magnetic resonance imaging (MRI). The comprehensive diagnostic possibilities of CT complemented by MRI will allow for a more sensitive detection, phenotype-driven characterization, and dedicated therapy monitoring of the disease. J. Magn. Reson. Imaging 2010;32:1340-1352. © 2010 Wiley-Liss, Inc. 
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