Decoding myofibroblast origins in human kidney fibrosis

Kidney fibrosis is the hallmark of chronic kidney disease progression; however, at present no antifibrotic therapies exist

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Main Authors: Kuppe, Christoph (Author) , Ibrahim, Mahmoud M. (Author) , Kranz, Jennifer (Author) , Zhang, Xiaoting (Author) , Ziegler, Susanne (Author) , Perales-Patón, Javier (Author) , Jansen, Jitske (Author) , Reimer, Katharina C. (Author) , Smith, James R. (Author) , Dobie, Ross (Author) , Wilson-Kanamori, John R. (Author) , Halder, Maurice (Author) , Xu, Yaoxian (Author) , Kabgani, Nazanin (Author) , Kaesler, Nadine (Author) , Klaus, Martin (Author) , Gernhold, Lukas (Author) , Puelles, Victor G. (Author) , Huber, Tobias (Author) , Boor, Peter (Author) , Menzel, Sylvia (Author) , Hoogenboezem, Remco M. (Author) , Bindels, Eric M. J. (Author) , Steffens, Joachim (Author) , Flöge, Jürgen (Author) , Schneider, Rebekka K. (Author) , Sáez Rodríguez, Julio (Author) , Henderson, Neil C. (Author) , Kramann, Rafael (Author)
Format: Article (Journal)
Language:English
Published: 14 January 2021
In: Nature
Year: 2021, Volume: 589, Pages: 281-286
ISSN:1476-4687
DOI:10.1038/s41586-020-2941-1
Online Access:Resolving-System, lizenzpflichtig: http://dx.doi.org/10.1038/s41586-020-2941-1
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Author Notes:Christoph Kuppe, Mahmoud M. Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C. Reimer, James R. Smith, Ross Dobie, John R. Wilson-Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G. Puelles, Tobias B. Huber, Peter Boor, Sylvia Menzel, Remco M. Hoogenboezem, Eric M. J. Bindels, Joachim Steffens, Jürgen Floege, Rebekka K. Schneider, Julio Saez-Rodriguez, Neil C. Henderson, Rafael Kramann
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Summary:Kidney fibrosis is the hallmark of chronic kidney disease progression; however, at present no antifibrotic therapies exist
Item Description:Gesehen am 02.05.2024
Online veröffentlicht: 11 November 2020
Physical Description:Online Resource
ISSN:1476-4687
DOI:10.1038/s41586-020-2941-1