Buchumschlag

Identification of potential interferents of methylmalonic acid: a previously unrecognized pitfall in clinical diagnostics and newborn screening

Determination of methylmalonic acid (MMA) from dried blood spots (DBS) is commonly performed in clinical diagnostics and newborn screening for propionic acidemia (PA) and methylmalonic acidemia. Isobaric compounds of MMA having the same mass can affect diagnostic reliability and quantitative results...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Monostori, Péter (VerfasserIn) , Godejohann, Markus (VerfasserIn) , Janda, Joachim (VerfasserIn) , Galla, Zsolt (VerfasserIn) , Rácz, Gábor (VerfasserIn) , Klinke, Glynis (VerfasserIn) , Szatmári, Ildikó (VerfasserIn) , Zsidegh, Petra (VerfasserIn) , Kohlmüller, Dirk (VerfasserIn) , Kölker, Stefan (VerfasserIn) , Hoffmann, Georg F. (VerfasserIn) , Gramer, Gwendolyn (VerfasserIn) , Okun, Jürgen G. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2023
In: Clinical biochemistry
Year: 2023, Jahrgang: 111, Pages: 72-80
ISSN:1873-2933
DOI:10.1016/j.clinbiochem.2022.09.010
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.clinbiochem.2022.09.010
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0009912022002247
Volltext
Verfasserangaben:Péter Monostori, Markus Godejohann, Joachim Janda, Zsolt Galla, Gábor Rácz, Glynis Klinke, Ildikó Szatmári, Petra Zsidegh, Dirk Kohlmüller, Stefan Kölker, Georg F. Hoffmann, Gwendolyn Gramer, Jürgen G. Okun

MARC

LEADER 00000caa a2200000 c 4500
001 1839345063
003 DE-627
005 20231116092451.0
007 cr uuu---uuuuu
008 230316s2023 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.clinbiochem.2022.09.010  |2 doi 
035 |a (DE-627)1839345063 
035 |a (DE-599)KXP1839345063 
035 |a (OCoLC)1389533056 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Monostori, Péter  |e VerfasserIn  |0 (DE-588)115672287X  |0 (DE-627)1019663952  |0 (DE-576)502395451  |4 aut 
245 1 0 |a Identification of potential interferents of methylmalonic acid  |b a previously unrecognized pitfall in clinical diagnostics and newborn screening  |c Péter Monostori, Markus Godejohann, Joachim Janda, Zsolt Galla, Gábor Rácz, Glynis Klinke, Ildikó Szatmári, Petra Zsidegh, Dirk Kohlmüller, Stefan Kölker, Georg F. Hoffmann, Gwendolyn Gramer, Jürgen G. Okun 
264 1 |c 2023 
300 |b Diagramme 
300 |a 9 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Online veröffentlicht am 3. Oktober 2022 
500 |a Gesehen am 16.11.2023 
520 |a Determination of methylmalonic acid (MMA) from dried blood spots (DBS) is commonly performed in clinical diagnostics and newborn screening for propionic acidemia (PA) and methylmalonic acidemia. Isobaric compounds of MMA having the same mass can affect diagnostic reliability and quantitative results, which represents a previously unrecognized pitfall in clinical assays for MMA. We set out to identify interfering substances of MMA in DBS, serum and urine samples from confirmed patients with PA and methylmalonic acidemia. 
650 4 |a Diagnostic reliability 
650 4 |a Interfering substance 
650 4 |a Mass spectrometry 
650 4 |a Metabolic disorder 
650 4 |a Methylmalonic acid 
650 4 |a Newborn screening 
700 1 |a Godejohann, Markus  |e VerfasserIn  |4 aut 
700 1 |a Janda, Joachim  |e VerfasserIn  |0 (DE-588)1195621736  |0 (DE-627)1677705108  |4 aut 
700 1 |a Galla, Zsolt  |e VerfasserIn  |4 aut 
700 1 |a Rácz, Gábor  |e VerfasserIn  |4 aut 
700 1 |a Klinke, Glynis  |d 1986-  |e VerfasserIn  |0 (DE-588)1120505895  |0 (DE-627)873446593  |0 (DE-576)480383197  |4 aut 
700 1 |a Szatmári, Ildikó  |e VerfasserIn  |4 aut 
700 1 |a Zsidegh, Petra  |e VerfasserIn  |4 aut 
700 1 |a Kohlmüller, Dirk  |d 1961-  |e VerfasserIn  |0 (DE-588)172724457  |0 (DE-627)697656500  |0 (DE-576)13358190X  |4 aut 
700 1 |a Kölker, Stefan  |e VerfasserIn  |0 (DE-588)1022937758  |0 (DE-627)717335771  |0 (DE-576)366197568  |4 aut 
700 1 |a Hoffmann, Georg F.  |d 1957-  |e VerfasserIn  |0 (DE-588)115652868  |0 (DE-627)077386116  |0 (DE-576)261230042  |4 aut 
700 1 |a Gramer, Gwendolyn  |d 1979-  |e VerfasserIn  |0 (DE-588)132278626  |0 (DE-627)520401697  |0 (DE-576)299048179  |4 aut 
700 1 |a Okun, Jürgen G.  |d 1968-  |e VerfasserIn  |0 (DE-588)121578232  |0 (DE-627)705551415  |0 (DE-576)292781296  |4 aut 
773 0 8 |i Enthalten in  |t Clinical biochemistry  |d Amsterdam [u.a.] : Elsevier Science, 1967  |g 111(2023) vom: Jan., Seite 72-80  |h Online-Ressource  |w (DE-627)306354764  |w (DE-600)1496880-0  |w (DE-576)094107882  |x 1873-2933  |7 nnas  |a Identification of potential interferents of methylmalonic acid a previously unrecognized pitfall in clinical diagnostics and newborn screening 
773 1 8 |g volume:111  |g year:2023  |g month:01  |g pages:72-80  |g extent:9  |a Identification of potential interferents of methylmalonic acid a previously unrecognized pitfall in clinical diagnostics and newborn screening 
856 4 0 |u https://doi.org/10.1016/j.clinbiochem.2022.09.010  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S0009912022002247  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20230316 
993 |a Article 
994 |a 2023 
998 |g 1120505895  |a Klinke, Glynis  |m 1120505895:Klinke, Glynis  |d 700000  |d 721000  |e 700000PK1120505895  |e 721000PK1120505895  |k 0/700000/  |k 1/700000/721000/  |p 6 
998 |g 121578232  |a Okun, Jürgen G.  |m 121578232:Okun, Jürgen G.  |d 910000  |d 910500  |d 50000  |e 910000PO121578232  |e 910500PO121578232  |e 50000PO121578232  |k 0/910000/  |k 1/910000/910500/  |k 0/50000/  |p 13  |y j 
998 |g 132278626  |a Gramer, Gwendolyn  |m 132278626:Gramer, Gwendolyn  |d 50000  |e 50000PG132278626  |k 0/50000/  |p 12 
998 |g 115652868  |a Hoffmann, Georg F.  |m 115652868:Hoffmann, Georg F.  |d 910000  |d 910500  |e 910000PH115652868  |e 910500PH115652868  |k 0/910000/  |k 1/910000/910500/  |p 11 
998 |g 1022937758  |a Kölker, Stefan  |m 1022937758:Kölker, Stefan  |d 910000  |d 910500  |d 50000  |e 910000PK1022937758  |e 910500PK1022937758  |e 50000PK1022937758  |k 0/910000/  |k 1/910000/910500/  |k 0/50000/  |p 10 
998 |g 172724457  |a Kohlmüller, Dirk  |m 172724457:Kohlmüller, Dirk  |d 910000  |d 910500  |e 910000PK172724457  |e 910500PK172724457  |k 0/910000/  |k 1/910000/910500/  |p 9 
998 |g 1195621736  |a Janda, Joachim  |m 1195621736:Janda, Joachim  |d 910000  |d 910500  |e 910000PJ1195621736  |e 910500PJ1195621736  |k 0/910000/  |k 1/910000/910500/  |p 3 
999 |a KXP-PPN1839345063  |e 4291347510 
BIB |a Y 
SER |a journal 
JSO |a {"recId":"1839345063","title":[{"title_sort":"Identification of potential interferents of methylmalonic acid","title":"Identification of potential interferents of methylmalonic acid","subtitle":"a previously unrecognized pitfall in clinical diagnostics and newborn screening"}],"id":{"eki":["1839345063"],"doi":["10.1016/j.clinbiochem.2022.09.010"]},"note":["Online veröffentlicht am 3. Oktober 2022","Gesehen am 16.11.2023"],"name":{"displayForm":["Péter Monostori, Markus Godejohann, Joachim Janda, Zsolt Galla, Gábor Rácz, Glynis Klinke, Ildikó Szatmári, Petra Zsidegh, Dirk Kohlmüller, Stefan Kölker, Georg F. Hoffmann, Gwendolyn Gramer, Jürgen G. Okun"]},"person":[{"family":"Monostori","roleDisplay":"VerfasserIn","given":"Péter","role":"aut","display":"Monostori, Péter"},{"role":"aut","display":"Godejohann, Markus","given":"Markus","roleDisplay":"VerfasserIn","family":"Godejohann"},{"roleDisplay":"VerfasserIn","family":"Janda","display":"Janda, Joachim","role":"aut","given":"Joachim"},{"given":"Zsolt","role":"aut","display":"Galla, Zsolt","roleDisplay":"VerfasserIn","family":"Galla"},{"family":"Rácz","roleDisplay":"VerfasserIn","role":"aut","display":"Rácz, Gábor","given":"Gábor"},{"family":"Klinke","roleDisplay":"VerfasserIn","given":"Glynis","role":"aut","display":"Klinke, Glynis"},{"given":"Ildikó","role":"aut","display":"Szatmári, Ildikó","family":"Szatmári","roleDisplay":"VerfasserIn"},{"family":"Zsidegh","roleDisplay":"VerfasserIn","given":"Petra","role":"aut","display":"Zsidegh, Petra"},{"roleDisplay":"VerfasserIn","family":"Kohlmüller","role":"aut","display":"Kohlmüller, Dirk","given":"Dirk"},{"family":"Kölker","roleDisplay":"VerfasserIn","given":"Stefan","role":"aut","display":"Kölker, Stefan"},{"display":"Hoffmann, Georg F.","role":"aut","given":"Georg F.","family":"Hoffmann","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","family":"Gramer","role":"aut","display":"Gramer, Gwendolyn","given":"Gwendolyn"},{"family":"Okun","roleDisplay":"VerfasserIn","given":"Jürgen G.","display":"Okun, Jürgen G.","role":"aut"}],"physDesc":[{"noteIll":"Diagramme","extent":"9 S."}],"relHost":[{"title":[{"title_sort":"Clinical biochemistry","title":"Clinical biochemistry","subtitle":"official journal of the Canadian Society of Clinical Chemists"}],"id":{"issn":["1873-2933"],"zdb":["1496880-0"],"eki":["306354764"]},"note":["Gesehen am 04.02.20"],"disp":"Identification of potential interferents of methylmalonic acid a previously unrecognized pitfall in clinical diagnostics and newborn screeningClinical biochemistry","part":{"pages":"72-80","extent":"9","year":"2023","volume":"111","text":"111(2023) vom: Jan., Seite 72-80"},"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"origin":[{"publisher":"Elsevier Science","publisherPlace":"Amsterdam [u.a.]","dateIssuedKey":"1967","dateIssuedDisp":"1967-"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["1.1967/68 -"],"corporate":[{"roleDisplay":"Herausgebendes Organ","display":"Canadian Society of Clinical Chemists","role":"isb"}],"recId":"306354764"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedKey":"2023","dateIssuedDisp":"2023"}],"language":["eng"]} 
SRT |a MONOSTORIPIDENTIFICA2023 

Ähnliche Einträge