Update on current treatments for adult acute myeloid leukemia: to treat acute myeloid leukemia intensively or non-intensively? That is the question
For several decades, the treatment for acute myeloid leukemia (AML) has been a dichotomous choice between intensive chemotherapy strategies with curative intent and non-intensive options including supportive care. Patients’ age and fitness, as well as comorbidities, primarily influenced this choice....
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February, 2023
|
| In: |
Haematologica
Year: 2023, Jahrgang: 108, Heft: 2, Pages: 342-352 |
| ISSN: | 1592-8721 |
| DOI: | 10.3324/haematol.2022.280802 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3324/haematol.2022.280802 Verlag, lizenzpflichtig, Volltext: https://haematologica.org/article/view/10947 
|
| Verfasserangaben: | Sonia Jaramillo and Richard F. Schlenk |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1839372532 | ||
| 003 | DE-627 | ||
| 005 | 20230706220100.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230316s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3324/haematol.2022.280802 |2 doi | |
| 035 | |a (DE-627)1839372532 | ||
| 035 | |a (DE-599)KXP1839372532 | ||
| 035 | |a (OCoLC)1389533055 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Jaramillo Segura, Sonia |e VerfasserIn |0 (DE-588)1149855606 |0 (DE-627)1010162772 |0 (DE-576)496412213 |4 aut | |
| 245 | 1 | 0 | |a Update on current treatments for adult acute myeloid leukemia |b to treat acute myeloid leukemia intensively or non-intensively? That is the question |c Sonia Jaramillo and Richard F. Schlenk |
| 264 | 1 | |c February, 2023 | |
| 300 | |a 11 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 16.03.2023 | ||
| 520 | |a For several decades, the treatment for acute myeloid leukemia (AML) has been a dichotomous choice between intensive chemotherapy strategies with curative intent and non-intensive options including supportive care. Patients’ age and fitness, as well as comorbidities, primarily influenced this choice. However, the therapeutic armamentarium is evolving, so that there are highly effective and increasingly specific drugs, fitting the mutational profile of a patient’s leukemia. There is now a spectrum of treatment options that are less intense and can be administered in an outpatient setting and to a substantial extent are equally or even more effective than standard intensive therapy. We are, therefore, witnessing a radical change in the treatment landscape of AML. In this review, we examine the current treatment options for patients with AML, considering the molecular spectrum of the disease on the background of patient-related factors. | ||
| 700 | 1 | |a Schlenk, Richard Friedrich |d 1965- |e VerfasserIn |0 (DE-588)129025380 |0 (DE-627)387778004 |0 (DE-576)297454102 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Haematologica |d Pavia : Ferrata Storti Foundation, 2014 |g 108(2023), 2 vom: Feb., Seite 342-352 |h Online-Ressource |w (DE-627)814204899 |w (DE-600)2805244-4 |w (DE-576)424051125 |x 1592-8721 |7 nnas |a Update on current treatments for adult acute myeloid leukemia to treat acute myeloid leukemia intensively or non-intensively? That is the question |
| 773 | 1 | 8 | |g volume:108 |g year:2023 |g number:2 |g month:02 |g pages:342-352 |g extent:11 |a Update on current treatments for adult acute myeloid leukemia to treat acute myeloid leukemia intensively or non-intensively? That is the question |
| 856 | 4 | 0 | |u https://doi.org/10.3324/haematol.2022.280802 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://haematologica.org/article/view/10947 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230316 | ||
| 993 | |a Article | ||
| 994 | |a 2023 | ||
| 998 | |g 129025380 |a Schlenk, Richard Friedrich |m 129025380:Schlenk, Richard Friedrich |d 910000 |d 910100 |e 910000PS129025380 |e 910100PS129025380 |k 0/910000/ |k 1/910000/910100/ |p 2 |y j | ||
| 998 | |g 1149855606 |a Jaramillo Segura, Sonia |m 1149855606:Jaramillo Segura, Sonia |d 910000 |d 910100 |e 910000PJ1149855606 |e 910100PJ1149855606 |k 0/910000/ |k 1/910000/910100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1839372532 |e 4291524773 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 16.03.2023"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"recId":"1839372532","person":[{"family":"Jaramillo Segura","given":"Sonia","roleDisplay":"VerfasserIn","display":"Jaramillo Segura, Sonia","role":"aut"},{"display":"Schlenk, Richard Friedrich","roleDisplay":"VerfasserIn","role":"aut","family":"Schlenk","given":"Richard Friedrich"}],"title":[{"title_sort":"Update on current treatments for adult acute myeloid leukemia","subtitle":"to treat acute myeloid leukemia intensively or non-intensively? That is the question","title":"Update on current treatments for adult acute myeloid leukemia"}],"physDesc":[{"extent":"11 S."}],"relHost":[{"title":[{"title_sort":"Haematologica","subtitle":"journal of the European Hematology Association : journal of the Ferrata Storti Foundation","title":"Haematologica"}],"pubHistory":["99.2014 -"],"part":{"issue":"2","pages":"342-352","year":"2023","extent":"11","volume":"108","text":"108(2023), 2 vom: Feb., Seite 342-352"},"titleAlt":[{"title":"journal of the European Hematology Association"}],"disp":"Update on current treatments for adult acute myeloid leukemia to treat acute myeloid leukemia intensively or non-intensively? That is the questionHaematologica","note":["Gesehen am 27.05.2022"],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"recId":"814204899","origin":[{"publisherPlace":"Pavia","dateIssuedDisp":"2014-","publisher":"Ferrata Storti Foundation","dateIssuedKey":"2014"}],"id":{"issn":["1592-8721"],"eki":["814204899"],"zdb":["2805244-4"]},"physDesc":[{"extent":"Online-Ressource"}]}],"name":{"displayForm":["Sonia Jaramillo and Richard F. Schlenk"]},"origin":[{"dateIssuedKey":"2023","dateIssuedDisp":"February, 2023"}],"id":{"doi":["10.3324/haematol.2022.280802"],"eki":["1839372532"]}} | ||
| SRT | |a JARAMILLOSUPDATEONCU2023 | ||