Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry
Precision oncology requires diagnostic accuracy and robust detection of actionable alterations. The Pediatric Targeted Therapy (PTT) 2.0 program aims at improving diagnostic accuracy by addition of molecular analyses to the existing histological diagnosis and detection of actionable alterations for...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 2023
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| In: |
European journal of cancer
Year: 2023, Volume: 180, Pages: 71-84 |
| ISSN: | 1879-0852 |
| DOI: | 10.1016/j.ejca.2022.11.015 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejca.2022.11.015 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0959804922017592 
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| Author Notes: | Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Capper, Nicola Dikow, Christian Sutter, Carina Müller, Romain Sigaud, Angelika Eggert, Thorsten Simon, Tim Niehues, Andreas von Deimling, Kristian W. Pajtler, Cornelis M. van Tilburg, David T. W. Jones, Felix Sahm, Stefan M. Pfister, Olaf Witt, Till Milde |
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| 245 | 1 | 0 | |a Molecular diagnostics enables detection of actionable targets |b the Pediatric Targeted Therapy 2.0 registry |c Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Capper, Nicola Dikow, Christian Sutter, Carina Müller, Romain Sigaud, Angelika Eggert, Thorsten Simon, Tim Niehues, Andreas von Deimling, Kristian W. Pajtler, Cornelis M. van Tilburg, David T. W. Jones, Felix Sahm, Stefan M. Pfister, Olaf Witt, Till Milde |
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| 520 | |a Precision oncology requires diagnostic accuracy and robust detection of actionable alterations. The Pediatric Targeted Therapy (PTT) 2.0 program aims at improving diagnostic accuracy by addition of molecular analyses to the existing histological diagnosis and detection of actionable alterations for relapsed paediatric oncology patients, in cases with limited availability of tumour material. | ||
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| 650 | 4 | |a Cancer predisposition | |
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| 650 | 4 | |a Molecular diagnostics | |
| 650 | 4 | |a Molecular targeted therapy | |
| 650 | 4 | |a Paediatric oncology | |
| 650 | 4 | |a Precision oncology | |
| 650 | 4 | |a Sarcoma | |
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