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Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation

External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gene expression. The analysis of such changes is complicated, as they consist of multi-layered temporal responses. While classical analy...

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Main Authors: Kowarsch, Andreas (Author) , Blöchl, Florian (Author) , Bohl, Sebastian (Author) , Saile, Maria (Author) , Gretz, Norbert (Author) , Klingmüller, Ursula (Author) , Theis, Fabian J. (Author)
Format: Article (Journal)
Language:English
Published: 30 November 2010
In: BMC bioinformatics
Year: 2010, Volume: 11, Pages: 1-14
ISSN:1471-2105
DOI:10.1186/1471-2105-11-585
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/1471-2105-11-585
Verlag, kostenfrei, Volltext: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-11-585
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Author Notes:Andreas Kowarsch, Florian Blöchl, Sebastian Bohl, Maria Saile, Norbert Gretz, Ursula Klingmüller, Fabian J. Theis

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