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Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas

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Histone methylation-modifiers, such as EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated whole genome and transcriptome data of 186 mature B-c...

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Main Authors: López, Cristina (Author) , Schleußner, Nikolai (Author) , Bernhart, Stephan H. (Author) , Kleinheinz, Kortine (Author) , Sungalee, Stephanie (Author) , Sczakiel, Henrike L. (Author) , Kretzmer, Helene (Author) , Toprak, Umut (Author) , Glaser, Selina (Author) , Wagener, Rabea (Author) , Ammerpohl, Ole (Author) , Bens, Susanne (Author) , Giefing, Maciej (Author) , González Sánchez, Juan Carlos (Author) , Apic, Gordana (Author) , Hübschmann, Daniel (Author) , Janz, Martin (Author) , Kreuz, Markus (Author) , Mottok, Anja (Author) , Muller, Judith M. (Author) , Seufert, Julian (Author) , Hoffmann, Steve (Author) , Korbel, Jan Oliver (Author) , Russell, Robert B. (Author) , Schule, Roland (Author) , Trumper, Lorenz (Author) , Klapper, Wolfram (Author) , Radlwimmer, Bernhard (Author) , Lichter, Peter (Author) , Kuppers, Ralf (Author) , Schlesner, Matthias (Author) , Mathas, Stephan (Author) , Siebert, Reiner (Author)
Format: Article (Journal)
Language:English
Published: February, 2023
In: Haematologica
Year: 2023, Volume: 108, Issue: 2, Pages: 543-554
ISSN:1592-8721
DOI:10.3324/haematol.2021.280005
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3324/haematol.2021.280005
Verlag, lizenzpflichtig, Volltext: https://haematologica.org/article/view/haematol.2021.280005
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Author Notes:Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hübschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Müller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas and Reiner Siebert and members of the ICGC MMML-Seq Consortium
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Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors by Bayındır-Buchhalter, İrem (Author) , Wolff, Gretchen (Author) , Lerch, Sarah (Author) , Sijmonsma, Tjeerd P. (Author) , Schuster, Maximilian (Author) , Gronych, Jan (Author) , Billeter, Adrian (Author) , Babaei, Rohollah (Author) , Krunic, Damir (Author) , Ruas, Jorge L. (Author) , Müller, Beat P. (Author) , Lichter, Peter (Author) , Herzig, Stephan (Author) , Vegiopoulos, Alexandros (Author) ,


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