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Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study

Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake. Accumulating evidence also indicates a role of ghrelin in cancer development.

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Main Authors: Campa, Daniele (Author) , Pardini, Barbara (Author) , Naccarati, Alessio (Author) , Vodickova, Ludmila (Author) , Novotny, Jan (Author) , Steinke, Verena (Author) , Rahner, Nils (Author) , Holinski-Feder, Elke (Author) , Morak, Monika (Author) , Schackert, Hans K. (Author) , Görgens, Heike (Author) , Kötting, Judith (Author) , Betz, Beate (Author) , Kloor, Matthias (Author) , Engel, Christoph (Author) , Büttner, Reinhard (Author) , Propping, Peter (Author) , Försti, Asta (Author) , Hemminki, Kari (Author) , Barale, Roberto (Author) , Vodicka, Pavel (Author) , Canzian, Federico (Author)
Format: Article (Journal)
Language:English
Published: 28 September 2010
In: BMC gastroenterology
Year: 2010, Volume: 10, Issue: 1, Pages: 1-6
ISSN:1471-230X
DOI:10.1186/1471-230X-10-112
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-230X-10-112
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Author Notes:Daniele Campa, Barbara Pardini, Alessio Naccarati, Ludmila Vodickova, Jan Novotny, Verena Steinke, Nils Rahner, Elke Holinski-Feder, Monika Morak, Hans K. Schackert, Heike Görgens, Judith Kötting, Beate Betz, Matthias Kloor, Christoph Engel, Reinhard Büttner, Peter Propping, Asta Försti, Kari Hemminki, Roberto Barale, Pavel Vodicka, Federico Canzian

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