Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism
Brain-derived neurotrophic factor (BDNF) has been implicated in a multitude of neurodevelopmental processes including neuronal differentiation, axonal outgrowth, synaptic plasticity, or survival. One human-specific single nucleotide polymorphism (rs6265) in the BDNF gene causes a substitution of val...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 2023
|
| In: |
Stem cell research
Year: 2023, Jahrgang: 66, Pages: 1-4 |
| ISSN: | 1876-7753 |
| DOI: | 10.1016/j.scr.2022.102989 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.scr.2022.102989 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1873506122003385 
|
| Verfasserangaben: | Sandra Horschitz, Josef Frank, Philipp Koch |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1840307544 | ||
| 003 | DE-627 | ||
| 005 | 20230706214708.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230328s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.scr.2022.102989 |2 doi | |
| 035 | |a (DE-627)1840307544 | ||
| 035 | |a (DE-599)KXP1840307544 | ||
| 035 | |a (OCoLC)1389530938 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Horschitz, Sandra |e VerfasserIn |0 (DE-588)1173627251 |0 (DE-627)1043471472 |0 (DE-576)515585742 |4 aut | |
| 245 | 1 | 0 | |a Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism |c Sandra Horschitz, Josef Frank, Philipp Koch |
| 264 | 1 | |c February 2023 | |
| 300 | |a 4 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online verfügbar 5 Dezember 2022 | ||
| 500 | |a Gesehen am 28.03.2023 | ||
| 520 | |a Brain-derived neurotrophic factor (BDNF) has been implicated in a multitude of neurodevelopmental processes including neuronal differentiation, axonal outgrowth, synaptic plasticity, or survival. One human-specific single nucleotide polymorphism (rs6265) in the BDNF gene causes a substitution of valine (Val) to methionine (Met) at codon 66 in the pro domain of the protein (Val66Met). This substitution is associated to reduced hippocampal volumes, poor performance on hippocampal-dependent memory tasks, and some mental disorders such as schizophrenia, depression or Alzheimer’s disease. Here we generated three iPSC lines from healthy donors, either homozygous (Val/Val and Met/Met) or heterozygous (Val/Met) for the polymorphism. | ||
| 700 | 1 | |a Frank, Josef |d 1972- |e VerfasserIn |0 (DE-588)1138799653 |0 (DE-627)896382850 |0 (DE-576)492700249 |4 aut | |
| 700 | 1 | |a Koch, Philipp |e VerfasserIn |0 (DE-588)1223723046 |0 (DE-627)1743250444 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Stem cell research |d Amsterdam [u.a.] : Elsevier, 2007 |g 66(2023) vom: Feb., Artikel-ID 102989, Seite 1-4 |h Online-Ressource |w (DE-627)548125856 |w (DE-600)2393143-7 |w (DE-576)284748463 |x 1876-7753 |7 nnas |a Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism |
| 773 | 1 | 8 | |g volume:66 |g year:2023 |g month:02 |g elocationid:102989 |g pages:1-4 |g extent:4 |a Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.scr.2022.102989 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S1873506122003385 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230328 | ||
| 993 | |a Article | ||
| 994 | |a 2023 | ||
| 998 | |g 1223723046 |a Koch, Philipp |m 1223723046:Koch, Philipp |d 60000 |e 60000PK1223723046 |k 0/60000/ |p 3 |y j | ||
| 998 | |g 1138799653 |a Frank, Josef |m 1138799653:Frank, Josef |d 60000 |e 60000PF1138799653 |k 0/60000/ |p 2 | ||
| 999 | |a KXP-PPN1840307544 |e 4298602567 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"title":[{"title":"Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism","title_sort":"Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism"}],"name":{"displayForm":["Sandra Horschitz, Josef Frank, Philipp Koch"]},"person":[{"given":"Sandra","role":"aut","display":"Horschitz, Sandra","family":"Horschitz"},{"display":"Frank, Josef","given":"Josef","role":"aut","family":"Frank"},{"display":"Koch, Philipp","role":"aut","given":"Philipp","family":"Koch"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"February 2023","dateIssuedKey":"2023"}],"recId":"1840307544","relHost":[{"pubHistory":["1.2007 -"],"part":{"text":"66(2023) vom: Feb., Artikel-ID 102989, Seite 1-4","year":"2023","volume":"66","extent":"4","pages":"1-4"},"language":["eng"],"title":[{"title_sort":"Stem cell research","title":"Stem cell research"}],"note":["Gesehen am 29.01.25","Fortsetzung der Druck-Ausgabe"],"disp":"Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphismStem cell research","physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1876-7753"],"zdb":["2393143-7"],"eki":["548125856"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"publisherPlace":"Amsterdam [u.a.]","dateIssuedKey":"2007","dateIssuedDisp":"2007-","publisher":"Elsevier"}],"recId":"548125856"}],"note":["Online verfügbar 5 Dezember 2022","Gesehen am 28.03.2023"],"physDesc":[{"extent":"4 S."}],"id":{"eki":["1840307544"],"doi":["10.1016/j.scr.2022.102989"]}} | ||
| SRT | |a HORSCHITZSGENERATION2023 | ||