β2-adrenergic stimulation blunts inhibition of epithelial ion transport by hypoxia of rat alveolar epithelial cells
Hypoxia impairs alveolar fluid clearance by inhibition of Na+ reabsorption, and also impairs β2 adrenergic signaling in alveolar epithelium. Since both are major rescue mechanisms preventing pulmonary edema, we studied whether acute and prolonged treatment with terbutaline would prevent hypoxic inhi...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2010
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| In: |
Cellular physiology and biochemistry
Year: 2010, Jahrgang: 25, Heft: 1, Pages: 123-134 |
| ISSN: | 1421-9778 |
| DOI: | 10.1159/000272057 |
| Online-Zugang: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1159/000272057 Verlag, kostenfrei, Volltext: https://www.karger.com/Article/FullText/272057 
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| Verfasserangaben: | Benjamin Loeh, Emel Baloglu, Alberto Ke, Peter Bärtsch and Heimo Mairbäurl |
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| 520 | |a Hypoxia impairs alveolar fluid clearance by inhibition of Na+ reabsorption, and also impairs β2 adrenergic signaling in alveolar epithelium. Since both are major rescue mechanisms preventing pulmonary edema, we studied whether acute and prolonged treatment with terbutaline would prevent hypoxic inhibition of ion transport. | ||
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