Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT
A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
21 May 2021
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| In: |
European journal of nuclear medicine and molecular imaging
Year: 2021, Jahrgang: 48, Heft: 12, Pages: 3918-3924 |
| ISSN: | 1619-7089 |
| DOI: | 10.1007/s00259-021-05374-4 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-021-05374-4 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00259-021-05374-4 |
| Verfasserangaben: | Stefan A. Koerber, R. Finck, K. Dendl, M. Uhl, T. Lindner, C. Kratochwil, M. Röhrich, H. Rathke, G. Ungerechts, S. Adeberg, K. Herfarth, D. Jaeger, J. Debus, U. Haberkorn, F.L. Giesel |
| Zusammenfassung: | A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a first clinical evaluation. |
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| Beschreibung: | Gesehen am 29.03.2023 |
| Beschreibung: | Online Resource |
| ISSN: | 1619-7089 |
| DOI: | 10.1007/s00259-021-05374-4 |