Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases
(1) Background: To assess dosimetry benefits of stereotactic magnetic resonance (MR)-guided online adaptive radiotherapy (SMART) of liver metastases. (2) Methods: This is a subgroup analysis of an ongoing prospective registry including patients with liver metastases. Patients were treated at the MRI...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
8 December 2022
|
| In: |
Cancers
Year: 2022, Jahrgang: 14, Heft: 24, Pages: 1-10 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers14246041 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers14246041 Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/14/24/6041 
|
| Verfasserangaben: | Fabian Weykamp, Efthimios Katsigiannopulos, Lars Piskorski, Sebastian Regnery, Philipp Hoegen, Jonas Ristau, C. Katharina Renkamp, Jakob Liermann, Tobias Forster, Kristin Lang, Laila König, Carolin Rippke, Carolin Buchele, Jürgen Debus, Sebastian Klüter and Juliane Hörner-Rieber |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 184205645X | ||
| 003 | DE-627 | ||
| 005 | 20250205103543.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230412s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/cancers14246041 |2 doi | |
| 035 | |a (DE-627)184205645X | ||
| 035 | |a (DE-599)KXP184205645X | ||
| 035 | |a (OCoLC)1389533909 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Weykamp, Fabian |d 1987- |e VerfasserIn |0 (DE-588)1072433036 |0 (DE-627)827655096 |0 (DE-576)43385992X |4 aut | |
| 245 | 1 | 0 | |a Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases |c Fabian Weykamp, Efthimios Katsigiannopulos, Lars Piskorski, Sebastian Regnery, Philipp Hoegen, Jonas Ristau, C. Katharina Renkamp, Jakob Liermann, Tobias Forster, Kristin Lang, Laila König, Carolin Rippke, Carolin Buchele, Jürgen Debus, Sebastian Klüter and Juliane Hörner-Rieber |
| 264 | 1 | |c 8 December 2022 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 12.04.2023 | ||
| 520 | |a (1) Background: To assess dosimetry benefits of stereotactic magnetic resonance (MR)-guided online adaptive radiotherapy (SMART) of liver metastases. (2) Methods: This is a subgroup analysis of an ongoing prospective registry including patients with liver metastases. Patients were treated at the MRIdian Linac between February 2020 and April 2022. The baseline plan was recalculated based on the updated anatomy of the day to generate the predicted plan. This predicted plan could then be re-optimized to create an adapted plan. (3) Results: Twenty-three patients received 30 SMART treatment series of in total 36 liver metastases. Most common primary tumors were colorectal- and pancreatic carcinoma (26.1% respectively). Most frequent fractionation scheme (46.6%) was 50 Gy in five fractions. The adapted plan was significantly superior compared to the predicted plan in regard to planning-target-volume (PTV) coverage, PTV overdosing, and organs-at-risk (OAR) dose constraints violations (91.5 vs. 38.0%, 6 vs. 19% and 0.6 vs. 10.0%; each p < 0.001). Plan adaptation significantly increased median BEDD95 by 3.2 Gy (p < 0.001). Mean total duration of SMART was 72.4 min. (4) Conclusions: SMART offers individualized ablative irradiation of liver metastases tailored to the daily anatomy with significant superior tumor coverage and improved sparing of OAR. | ||
| 650 | 4 | |a liver metastases | |
| 650 | 4 | |a MR-guided | |
| 650 | 4 | |a stereotactic body radiotherapy (SBRT) | |
| 650 | 4 | |a stereotactic MR-guided adaptive radiotherapy | |
| 700 | 1 | |a Katsigiannopulos, Efthimios |e VerfasserIn |0 (DE-588)1296062392 |0 (DE-627)1852744413 |4 aut | |
| 700 | 1 | |a Piskorski, Lars |d 1998- |e VerfasserIn |0 (DE-588)1354770218 |0 (DE-627)1915936438 |4 aut | |
| 700 | 1 | |a Regnery, Sebastian |e VerfasserIn |0 (DE-588)1182554776 |0 (DE-627)1662804199 |4 aut | |
| 700 | 1 | |a Hoegen-Saßmannshausen, Philipp |d 1987- |e VerfasserIn |0 (DE-588)1162715278 |0 (DE-627)1026887836 |0 (DE-576)507591283 |4 aut | |
| 700 | 1 | |a Ristau, Jonas |d 1989- |e VerfasserIn |0 (DE-588)1075216303 |0 (DE-627)83302986X |0 (DE-576)443326444 |4 aut | |
| 700 | 1 | |a Renkamp, Claudia Katharina |d 1990- |e VerfasserIn |0 (DE-588)1153576384 |0 (DE-627)101508625X |0 (DE-576)500325286 |4 aut | |
| 700 | 1 | |a Liermann, Jakob |d 1989- |e VerfasserIn |0 (DE-588)1147779287 |0 (DE-627)1007181842 |0 (DE-576)496034170 |4 aut | |
| 700 | 1 | |a Forster, Tobias |d 1986- |e VerfasserIn |0 (DE-588)1102961132 |0 (DE-627)860567028 |0 (DE-576)470399430 |4 aut | |
| 700 | 1 | |a Uzun-Lang, Kristin |d 1986- |e VerfasserIn |0 (DE-588)106868237X |0 (DE-627)820592064 |0 (DE-576)428008569 |4 aut | |
| 700 | 1 | |a König, Laila |d 1986- |e VerfasserIn |0 (DE-588)1053640579 |0 (DE-627)790403315 |0 (DE-576)409584282 |4 aut | |
| 700 | 1 | |a Rippke, Carolin |d 1993- |e VerfasserIn |0 (DE-588)1238772773 |0 (DE-627)1766392539 |4 aut | |
| 700 | 1 | |a Buchele, Carolin |d 1992- |e VerfasserIn |0 (DE-588)1238773230 |0 (DE-627)1766395635 |4 aut | |
| 700 | 1 | |a Debus, Jürgen |d 1964- |e VerfasserIn |0 (DE-588)1022671421 |0 (DE-627)717025780 |0 (DE-576)365774944 |4 aut | |
| 700 | 1 | |a Klüter, Sebastian |d 1980- |e VerfasserIn |0 (DE-588)1071160796 |0 (DE-627)825622646 |0 (DE-576)311255248 |4 aut | |
| 700 | 1 | |a Hörner-Rieber, Juliane |d 1985- |e VerfasserIn |0 (DE-588)1025307631 |0 (DE-627)722020511 |0 (DE-576)370188039 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cancers |d Basel : MDPI, 2009 |g 14(2022), 24, Artikel-ID 6041, Seite 1-10 |h Online-Ressource |w (DE-627)614095670 |w (DE-600)2527080-1 |w (DE-576)313958548 |x 2072-6694 |7 nnas |a Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases |
| 773 | 1 | 8 | |g volume:14 |g year:2022 |g number:24 |g elocationid:6041 |g pages:1-10 |g extent:10 |a Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases |
| 856 | 4 | 0 | |u https://doi.org/10.3390/cancers14246041 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.mdpi.com/2072-6694/14/24/6041 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230412 | ||
| 993 | |a Article | ||
| 994 | |a 2022 | ||
| 998 | |g 1025307631 |a Hörner-Rieber, Juliane |m 1025307631:Hörner-Rieber, Juliane |d 910000 |d 911400 |d 50000 |e 910000PH1025307631 |e 911400PH1025307631 |e 50000PH1025307631 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 16 |y j | ||
| 998 | |g 1071160796 |a Klüter, Sebastian |m 1071160796:Klüter, Sebastian |d 910000 |d 911400 |d 50000 |e 910000PK1071160796 |e 911400PK1071160796 |e 50000PK1071160796 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 15 | ||
| 998 | |g 1022671421 |a Debus, Jürgen |m 1022671421:Debus, Jürgen |d 910000 |d 911400 |d 50000 |d 130000 |e 910000PD1022671421 |e 911400PD1022671421 |e 50000PD1022671421 |e 130000PD1022671421 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |k 0/130000/ |p 14 | ||
| 998 | |g 1238773230 |a Buchele, Carolin |m 1238773230:Buchele, Carolin |d 910000 |d 911400 |e 910000PB1238773230 |e 911400PB1238773230 |k 0/910000/ |k 1/910000/911400/ |p 13 | ||
| 998 | |g 1238772773 |a Rippke, Carolin |m 1238772773:Rippke, Carolin |d 910000 |d 911400 |e 910000PR1238772773 |e 911400PR1238772773 |k 0/910000/ |k 1/910000/911400/ |p 12 | ||
| 998 | |g 1053640579 |a König, Laila |m 1053640579:König, Laila |d 910000 |d 911400 |d 50000 |e 910000PK1053640579 |e 911400PK1053640579 |e 50000PK1053640579 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 11 | ||
| 998 | |g 106868237X |a Uzun-Lang, Kristin |m 106868237X:Uzun-Lang, Kristin |d 910000 |d 911400 |d 50000 |e 910000PU106868237X |e 911400PU106868237X |e 50000PU106868237X |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 10 | ||
| 998 | |g 1102961132 |a Forster, Tobias |m 1102961132:Forster, Tobias |d 910000 |d 911400 |d 50000 |e 910000PF1102961132 |e 911400PF1102961132 |e 50000PF1102961132 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 9 | ||
| 998 | |g 1147779287 |a Liermann, Jakob |m 1147779287:Liermann, Jakob |d 910000 |d 911400 |d 50000 |e 910000PL1147779287 |e 911400PL1147779287 |e 50000PL1147779287 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 8 | ||
| 998 | |g 1153576384 |a Renkamp, Claudia Katharina |m 1153576384:Renkamp, Claudia Katharina |d 910000 |d 911400 |e 910000PR1153576384 |e 911400PR1153576384 |k 0/910000/ |k 1/910000/911400/ |p 7 | ||
| 998 | |g 1075216303 |a Ristau, Jonas |m 1075216303:Ristau, Jonas |d 910000 |d 911400 |d 50000 |e 910000PR1075216303 |e 911400PR1075216303 |e 50000PR1075216303 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 6 | ||
| 998 | |g 1162715278 |a Hoegen-Saßmannshausen, Philipp |m 1162715278:Hoegen-Saßmannshausen, Philipp |d 910000 |d 911400 |d 50000 |e 910000PH1162715278 |e 911400PH1162715278 |e 50000PH1162715278 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 5 | ||
| 998 | |g 1182554776 |a Regnery, Sebastian |m 1182554776:Regnery, Sebastian |d 910000 |d 911400 |d 50000 |e 910000PR1182554776 |e 911400PR1182554776 |e 50000PR1182554776 |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 4 | ||
| 998 | |g 1354770218 |a Piskorski, Lars |m 1354770218:Piskorski, Lars |d 50000 |e 50000PP1354770218 |k 0/50000/ |p 3 | ||
| 998 | |g 1296062392 |a Katsigiannopulos, Efthimios |m 1296062392:Katsigiannopulos, Efthimios |d 50000 |e 50000PK1296062392 |k 0/50000/ |p 2 | ||
| 998 | |g 1072433036 |a Weykamp, Fabian |m 1072433036:Weykamp, Fabian |d 910000 |d 911400 |e 910000PW1072433036 |e 911400PW1072433036 |k 0/910000/ |k 1/910000/911400/ |p 1 |x j | ||
| 999 | |a KXP-PPN184205645X |e 4307694880 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"184205645X","physDesc":[{"extent":"10 S."}],"title":[{"title":"Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases","title_sort":"Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastases"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"note":["Gesehen am 12.04.2023"],"origin":[{"dateIssuedDisp":"8 December 2022","dateIssuedKey":"2022"}],"person":[{"family":"Weykamp","role":"aut","given":"Fabian","display":"Weykamp, Fabian"},{"display":"Katsigiannopulos, Efthimios","role":"aut","given":"Efthimios","family":"Katsigiannopulos"},{"display":"Piskorski, Lars","given":"Lars","role":"aut","family":"Piskorski"},{"family":"Regnery","role":"aut","given":"Sebastian","display":"Regnery, Sebastian"},{"family":"Hoegen-Saßmannshausen","role":"aut","given":"Philipp","display":"Hoegen-Saßmannshausen, Philipp"},{"family":"Ristau","role":"aut","given":"Jonas","display":"Ristau, Jonas"},{"given":"Claudia Katharina","role":"aut","family":"Renkamp","display":"Renkamp, Claudia Katharina"},{"given":"Jakob","role":"aut","family":"Liermann","display":"Liermann, Jakob"},{"display":"Forster, Tobias","given":"Tobias","role":"aut","family":"Forster"},{"role":"aut","given":"Kristin","family":"Uzun-Lang","display":"Uzun-Lang, Kristin"},{"family":"König","role":"aut","given":"Laila","display":"König, Laila"},{"family":"Rippke","given":"Carolin","role":"aut","display":"Rippke, Carolin"},{"display":"Buchele, Carolin","family":"Buchele","given":"Carolin","role":"aut"},{"display":"Debus, Jürgen","family":"Debus","role":"aut","given":"Jürgen"},{"display":"Klüter, Sebastian","family":"Klüter","given":"Sebastian","role":"aut"},{"display":"Hörner-Rieber, Juliane","role":"aut","given":"Juliane","family":"Hörner-Rieber"}],"relHost":[{"origin":[{"publisherPlace":"Basel","dateIssuedKey":"2009","dateIssuedDisp":"2009-","publisher":"MDPI"}],"title":[{"title":"Cancers","title_sort":"Cancers"}],"note":["Gesehen am 27.05.2020"],"type":{"media":"Online-Ressource","bibl":"periodical"},"language":["eng"],"recId":"614095670","physDesc":[{"extent":"Online-Ressource"}],"disp":"Dosimetric benefit of adaptive magnetic resonance-guided stereotactic body radiotherapy of liver metastasesCancers","pubHistory":["1.2009 -"],"name":{"displayForm":["Molecular Diversity Preservation International (MDPI)"]},"part":{"issue":"24","text":"14(2022), 24, Artikel-ID 6041, Seite 1-10","extent":"10","pages":"1-10","volume":"14","year":"2022"},"id":{"zdb":["2527080-1"],"eki":["614095670"],"issn":["2072-6694"]}}],"id":{"doi":["10.3390/cancers14246041"],"eki":["184205645X"]},"name":{"displayForm":["Fabian Weykamp, Efthimios Katsigiannopulos, Lars Piskorski, Sebastian Regnery, Philipp Hoegen, Jonas Ristau, C. Katharina Renkamp, Jakob Liermann, Tobias Forster, Kristin Lang, Laila König, Carolin Rippke, Carolin Buchele, Jürgen Debus, Sebastian Klüter and Juliane Hörner-Rieber"]}} | ||
| SRT | |a WEYKAMPFABDOSIMETRIC8202 | ||