Repeated low-dose computed tomography in current and former smokers for quantification of emphysema
Objective: - To quantify different emphysema evolution in current and former smokers. - Methods: - We retrospectively analyzed low-dose computed tomography scans from a lung cancer screening study of 59 current and 75 former smokers. The quantitative emphysema analysi...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2010
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| In: |
Journal of computer assisted tomography
Year: 2010, Jahrgang: 34, Heft: 6, Pages: 933-938 |
| ISSN: | 1532-3145 |
| DOI: | 10.1097/RCT.0b013e3181ef9fbe |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/RCT.0b013e3181ef9fbe Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/jcat/Fulltext/2010/11000/Repeated_Low_Dose_Computed_Tomography_in_Current.21.aspx 
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| Verfasserangaben: | Alexander McGregor, Heidi C. Roberts, MD, Zhi Dong, MD, Ravi Menezes, PhD, Hans-Ulrich Kauczor, MD, Oliver Weinheimer, MD, and Claus Peter Heussel, MD |
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| 245 | 1 | 0 | |a Repeated low-dose computed tomography in current and former smokers for quantification of emphysema |c Alexander McGregor, Heidi C. Roberts, MD, Zhi Dong, MD, Ravi Menezes, PhD, Hans-Ulrich Kauczor, MD, Oliver Weinheimer, MD, and Claus Peter Heussel, MD |
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| 520 | |a Objective: - To quantify different emphysema evolution in current and former smokers. - Methods: - We retrospectively analyzed low-dose computed tomography scans from a lung cancer screening study of 59 current and 75 former smokers. The quantitative emphysema analysis was performed using a home-built software (YACTA version 0.9), yielding the parameters lung volume, emphysema volume (EV), emphysema index (EI), mean lung density, and 15th percentile. - Results: - The baseline EV and EI were significantly different (median EVformer =422 mL vs EVcurrent =249 mL, P = 0.0003; and median EIformer =7.6 % vs EIcurrent =4.1 %, P = 0.0001, respectively). On the annual repeat scan, the median EI and EV for former smokers had decreased significantly (ΔEIformer = −0.257%, P = 0.004; and ΔEVcurrent = −0.203 mL, P = 0.020), whereas there was no emphysema change in current smokers. - Conclusions: - We were able to demonstrate different emphysema evolution in current versus former smokers; emphysema parameters decreased in the former smokers and remained stable in current smokers. | ||
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| 700 | 1 | |a Dong, Zhi |e VerfasserIn |4 aut | |
| 700 | 1 | |a Menezes, Ravi |e VerfasserIn |4 aut | |
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