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MXD/MIZ1 transcription regulatory complexes activate the expression of MYC-repressed genes

MXDs are transcription repressors that antagonize MYC-mediated gene activation. MYC, when associated with MIZ1, acts also as a repressor of a subset of genes, including p15 and p21. A role for MXDs in regulation of MYC-repressed genes is not known. We report that MXDs activate transcription of p15 a...

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Hauptverfasser: Shostak, Anton (VerfasserIn) , Schermann, Géza (VerfasserIn) , Diernfellner, Axel (VerfasserIn) , Brunner, Michael (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2021
In: FEBS letters
Year: 2021, Jahrgang: 595, Heft: 12, Pages: 1639-1655
ISSN:1873-3468
DOI:10.1002/1873-3468.14097
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/1873-3468.14097
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.14097
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Verfasserangaben:Anton Shostak, Géza Schermann, Axel Diernfellner and Michael Brunner

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