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New trends for staging and therapy for localized gastroesophageal cancer: the role of PET

Treatment options for localized gastroesophageal cancers reach from limited resection to multimodality treatment. Accurate clinical assessment, prognostic and predictive information are needed to select the most appropriate treatment approach. Positron emission tomography (PET) in combination with c...

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Bibliographic Details
Main Authors: Lordick, Florian (Author) , Ott, Katja (Author) , Krause, Bernd Joachim (Author)
Format: Article (Journal)
Language:English
Published: 2010
In: Annals of oncology
Year: 2010, Volume: 21, Pages: vii294-vii299
ISSN:1569-8041
DOI:10.1093/annonc/mdq289
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/annonc/mdq289
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0923753419396966
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Author Notes:F. Lordick, K. Ott & B.J. Krause
Description
Summary:Treatment options for localized gastroesophageal cancers reach from limited resection to multimodality treatment. Accurate clinical assessment, prognostic and predictive information are needed to select the most appropriate treatment approach. Positron emission tomography (PET) in combination with computed tomography (CT) in a hybrid imaging modality PET-CT may refine the staging accuracy and add prognostic information. Moreover, experiences from diverse centers indicate that PET also might improve significantly the assessment of response to preoperative chemotherapy and chemoradiotherapy. This article outlines the current value of PET in the staging and multidisciplinary care of gastroesophageal cancer. At this stage, it remains unclear whether the prognosis of patients can be improved by implementing PET in the management of localized disease. Prospective multicenter studies have to be carried out to validate metabolic cut-off values and to prove the benefit of PET-guided treatment decisions.
Item Description:Online veröffentlicht am 6. Januar 2020
Gesehen am 18.04.2023
Physical Description:Online Resource
ISSN:1569-8041
DOI:10.1093/annonc/mdq289

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