Rationale and design of the FreezeAF trial: a randomized controlled noninferiority trial comparing isolation of the pulmonary veins with the cryoballoon catheter versus open irrigated radiofrequency ablation in patients with paroxysmal atrial fibrillation

Atrial fibrillation is the most commonly encountered clinical arrhythmia, and there are an increasing number of patients with paroxysmal atrial fibrillation treated by catheter ablation. The criterion standard is the isolation of the pulmonary veins (PVs) using radiofrequency (RF) energy in combinat...

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Hauptverfasser: Luik, Armin (VerfasserIn) , Merkel, Matthias (VerfasserIn) , Hoeren, Danielle (VerfasserIn) , Riexinger, Tobias (VerfasserIn) , Kieser, Meinhard (VerfasserIn) , Schmitt, Claus (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1 April 2010
In: American heart journal
Year: 2010, Jahrgang: 159, Heft: 4, Pages: 555-560.e1
ISSN:1097-6744
DOI:10.1016/j.ahj.2010.01.008
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ahj.2010.01.008
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002870310000797
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Verfasserangaben:Armin Luik, Matthias Merkel, Danielle Hoeren, Tobias Riexinger, Meinhard Kieser, and Claus Schmitt

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520 |a Atrial fibrillation is the most commonly encountered clinical arrhythmia, and there are an increasing number of patients with paroxysmal atrial fibrillation treated by catheter ablation. The criterion standard is the isolation of the pulmonary veins (PVs) using radiofrequency (RF) energy in combination with an open irrigated tip catheter. The procedure remains technically challenging with a significant number of complications. So far, no randomized comparisons between the outcome of cryoballoon versus RF ablation are available. 
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