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A novel subgroup of UCHL1-related cancers is associated with genomic instability and sensitivity to DNA-damaging treatment

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Purpose: Identification of molecularly-defined cancer subgroups and targeting tumor-specific vulnerabilities have a strong potential to improve treatment response and patient outcomes but remain an unmet challenge of high clinical relevance, especially in head and neck squamous cell carcinoma (HNSC)...

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Main Authors: Burkart, Sebastian (Author) , Weusthof, Christopher (Author) , Khorani, Karam (Author) , Steen, Sonja (Author) , Stögbauer, Fabian (Author) , Unger, Kristian (Author) , Hess, Julia (Author) , Zitzelsberger, Horst (Author) , Belka, Claus (Author) , Kurth, Ina (Author) , Heß, Jochen (Author)
Format: Article (Journal)
Language:English
Published: 8 March 2023
In: Cancers
Year: 2023, Volume: 15, Issue: 6, Pages: 1-16
ISSN:2072-6694
DOI:10.3390/cancers15061655
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers15061655
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/15/6/1655
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Author Notes:Sebastian Burkart, Christopher Weusthof, Karam Khorani, Sonja Steen, Fabian Stögbauer, Kristian Unger, Julia Hess, Horst Zitzelsberger, Claus Belka, Ina Kurth and Jochen Hess
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Expansion of the phenotypic and genotypic spectrum for PRKAR1B-related Marbach-Schaaf neurodevelopmental syndrome: a case series by Burkart, Sebastian (Author) , Guzeloglu, Tarik (Author) , Soares, Ana R. (Author) , Valenzuela, Irene (Author) , Tizzano, Eduardo F. (Author) , Gómez-Andres, David (Author) , Pasquier, Laurent (Author) , Legendre, Marine (Author) , Berges, Camille (Author) , Thevenon, Julien (Author) , Gauthier, Marjolaine (Author) , Heid, Caleb (Author) , Ranum, Elly (Author) , Shen, Joseph (Author) , Frees, Michelle (Author) , Schmidtke, Michael W. (Author) , Caro, Pilar (Author) , Schaaf, Christian P. (Author) ,


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