Magnetic resonance neurography for the diagnosis of extrapelvic sciatic endometriosis

Objective - To illustrate magnetic resonance neurography findings of severe sciatic injury and muscle denervation related to deep gluteal endometriosis at the sciatic notch. - Design - Case report. - Setting - Academic teaching hospital. - Patient(s) - A 39-year-old woman with a 4-year history of sc...

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Hauptverfasser: Pham, Mirko (VerfasserIn) , Sommer, Claudia (VerfasserIn) , Wessig, Carsten (VerfasserIn) , Monoranu, Camelia-Maria (VerfasserIn) , Pérez, José (VerfasserIn) , Stoll, Guido (VerfasserIn) , Bendszus, Martin (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 10 February 2010
In: Fertility and sterility
Year: 2010, Jahrgang: 94, Heft: 1, Pages: 351.e11-351.e14
ISSN:1556-5653
DOI:10.1016/j.fertnstert.2009.12.046
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.fertnstert.2009.12.046
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0015028209042952
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Verfasserangaben:Mirko Pham, Claudia Sommer, Carsten Wessig, Camelia-Maria Monoranu, José Pérez, Guido Stoll, and Martin Bendszus
Beschreibung
Zusammenfassung:Objective - To illustrate magnetic resonance neurography findings of severe sciatic injury and muscle denervation related to deep gluteal endometriosis at the sciatic notch. - Design - Case report. - Setting - Academic teaching hospital. - Patient(s) - A 39-year-old woman with a 4-year history of sciatica related to the menstrual cycle. - Intervention(s) - Surgical exploration of the sciatic notch for diagnostic confirmation, external neurolysis of the sciatic nerve, and eventual pharmacologic treatment. - Main Outcome Measure(s) - Magnetic resonance neurography imaging revealed severe neuropathic injury and muscle denervation related to a deep infiltrative endometriotic focus at the sciatic notch, which was confirmed histologically on surgical exploration. Detailed electrodiagnostic and clinical neurologic examinations at initial presentation and during follow-up were obtained for further assessment of nerve degeneration, muscle denervation, and clinical recovery. - Result(s) - Initial gynecologic and eventual laparoscopic evaluation on persisting complaints were without pathological findings. When a progressive weakness of the leg was noted, magnetic resonance neurography revealed a severe axonal damage to the sciatic nerve and denervation of distal target muscles related to a diffuse infiltrative lesion at the sciatic notch. On surgical exploration, extragenital endometriosis was confirmed histologically. Considerable improvement in pain and strength occurred after pharmacologic therapy with a GnRH analogue. - Conclusion(s) - This is the first report to describe imaging findings of magnetic resonance neurography in severe neuropathic injury of the sciatic nerve and subsequent muscle denervation related to a deep infiltrative gluteal endometriotic focus.
Beschreibung:Gesehen am 03.05.2023
Beschreibung:Online Resource
ISSN:1556-5653
DOI:10.1016/j.fertnstert.2009.12.046