Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma: a potential alternative to the Patlak model of CT perfusion
Introduction - By using bolus tracking with an appropriate acquisition delay dual-energy computed tomography (DECT) iodine maps might serve as a replacement of CT perfusion maps at reduced radiation exposure. This study aimed to evaluate the optimal acquisition delays of DECT for the replacement of...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
April 2023
|
| In: |
Heliyon
Year: 2023, Jahrgang: 9, Heft: 4, Pages: 1-12 |
| ISSN: | 2405-8440 |
| DOI: | 10.1016/j.heliyon.2023.e14726 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.heliyon.2023.e14726 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2405844023019333 
|
| Verfasserangaben: | Stephan Skornitzke, Philipp Mayer, Hans-Ulrich Kauczor, Wolfram Stiller |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1844484378 | ||
| 003 | DE-627 | ||
| 005 | 20240327080247.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230503s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.heliyon.2023.e14726 |2 doi | |
| 035 | |a (DE-627)1844484378 | ||
| 035 | |a (DE-599)KXP1844484378 | ||
| 035 | |a (OCoLC)1389530466 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Skornitzke, Stephan |d 1987- |e VerfasserIn |0 (DE-588)1110072589 |0 (DE-627)864783523 |0 (DE-576)475718267 |4 aut | |
| 245 | 1 | 0 | |a Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma |b a potential alternative to the Patlak model of CT perfusion |c Stephan Skornitzke, Philipp Mayer, Hans-Ulrich Kauczor, Wolfram Stiller |
| 264 | 1 | |c April 2023 | |
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 03.05.2023 | ||
| 520 | |a Introduction - By using bolus tracking with an appropriate acquisition delay dual-energy computed tomography (DECT) iodine maps might serve as a replacement of CT perfusion maps at reduced radiation exposure. This study aimed to evaluate the optimal acquisition delays of DECT for the replacement of parameter maps calculated with the Patlak model in pancreatic adenocarcinoma by corresponding iodine maps. - Materials and methods - Dual-source dynamic DECT acquisitions at 80 kVp/Sn140 kVp of 14 patients with pancreatic carcinoma were used to calculate CT perfusion maps of blood volume and permeability with the Patlak model. DECT iodine maps were generated from individual DECT acquisitions, matching acquisition times relative to prior bolus-triggered three-phase CT acquisitions for investigating different acquisition delays. Correlation between perfusion parameters and iodine concentrations was determined for acquisition delays between −6 s and 33 s. - Results - Correlation between iodine concentrations and perfusion parameters ranged from −0.05 to 0.63 for blood volume and from −0.05 to 0.71 for permeability, depending on potential trigger delay. The correlation was significant for potential acquisition delays above 1.5 s for blood volume and above 9.0 s for permeability (both p < 0.05). Maximum correlation occurred at an acquisition delay of 15.0 s for blood volume (r = 0.63) and at 25.5 s for permeability (r = 0.71), with significantly lower iodine concentrations in carcinoma (15.0 s: 1.3 ± 0.5 mg/ml; 22.5 s: 1.4 ± 0.7 mg/ml) than in non-neoplastic pancreatic parenchyma (15.0 s: 2.3 ± 0.8 mg/ml; 22.5 s: 2.4 ± 0.6 mg/ml; p < 0.05). - Discussion - In the future, well-timed DECT iodine maps acquired with bolus tracking could provide an alternative to permeability and blood volume maps calculated with the Patlak model. | ||
| 650 | 4 | |a CT perfusion | |
| 650 | 4 | |a Dual-energy CT | |
| 650 | 4 | |a Iodine quantification | |
| 650 | 4 | |a Pancreatic carcinoma | |
| 700 | 1 | |a Mayer, Philipp |d 1985- |e VerfasserIn |0 (DE-588)1066605440 |0 (DE-627)817714758 |0 (DE-576)426052250 |4 aut | |
| 700 | 1 | |a Kauczor, Hans-Ulrich |d 1962- |e VerfasserIn |0 (DE-588)139267123 |0 (DE-627)70327113X |0 (DE-576)310955327 |4 aut | |
| 700 | 1 | |a Stiller, Wolfram |d 1976- |e VerfasserIn |0 (DE-588)105822672X |0 (DE-627)796627495 |0 (DE-576)414249496 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Heliyon |d London [u.a.] : Elsevier, 2015 |g 9(2023), 4 vom: Apr., Artikel-ID e14726, Seite 1-12 |h Online-Ressource |w (DE-627)835893197 |w (DE-600)2835763-2 |w (DE-576)445959371 |x 2405-8440 |7 nnas |a Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma a potential alternative to the Patlak model of CT perfusion |
| 773 | 1 | 8 | |g volume:9 |g year:2023 |g number:4 |g month:04 |g elocationid:e14726 |g pages:1-12 |g extent:12 |a Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma a potential alternative to the Patlak model of CT perfusion |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.heliyon.2023.e14726 |x Resolving-System |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S2405844023019333 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20230503 | ||
| 993 | |a Article | ||
| 994 | |a 2023 | ||
| 998 | |g 105822672X |a Stiller, Wolfram |m 105822672X:Stiller, Wolfram |d 910000 |d 911400 |d 50000 |e 910000PS105822672X |e 911400PS105822672X |e 50000PS105822672X |k 0/910000/ |k 1/910000/911400/ |k 0/50000/ |p 4 |y j | ||
| 998 | |g 139267123 |a Kauczor, Hans-Ulrich |m 139267123:Kauczor, Hans-Ulrich |d 910000 |d 911400 |e 910000PK139267123 |e 911400PK139267123 |k 0/910000/ |k 1/910000/911400/ |p 3 | ||
| 998 | |g 1066605440 |a Mayer, Philipp |m 1066605440:Mayer, Philipp |d 910000 |d 911400 |e 910000PM1066605440 |e 911400PM1066605440 |k 0/910000/ |k 1/910000/911400/ |p 2 | ||
| 998 | |g 1110072589 |a Skornitzke, Stephan |m 1110072589:Skornitzke, Stephan |d 50000 |e 50000PS1110072589 |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1844484378 |e 4317638371 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1844484378","person":[{"role":"aut","family":"Skornitzke","display":"Skornitzke, Stephan","given":"Stephan"},{"given":"Philipp","display":"Mayer, Philipp","role":"aut","family":"Mayer"},{"family":"Kauczor","role":"aut","display":"Kauczor, Hans-Ulrich","given":"Hans-Ulrich"},{"given":"Wolfram","display":"Stiller, Wolfram","role":"aut","family":"Stiller"}],"note":["Gesehen am 03.05.2023"],"language":["eng"],"name":{"displayForm":["Stephan Skornitzke, Philipp Mayer, Hans-Ulrich Kauczor, Wolfram Stiller"]},"relHost":[{"pubHistory":["1.2015 -"],"note":["Gesehen am 28.05.20"],"part":{"year":"2023","volume":"9","issue":"4","pages":"1-12","extent":"12","text":"9(2023), 4 vom: Apr., Artikel-ID e14726, Seite 1-12"},"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma a potential alternative to the Patlak model of CT perfusionHeliyon","recId":"835893197","origin":[{"publisherPlace":"London [u.a.]","dateIssuedKey":"2015","dateIssuedDisp":"2015-","publisher":"Elsevier"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["835893197"],"issn":["2405-8440"],"zdb":["2835763-2"]},"title":[{"title_sort":"Heliyon","title":"Heliyon"}]}],"origin":[{"dateIssuedDisp":"April 2023","dateIssuedKey":"2023"}],"title":[{"title":"Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma","subtitle":"a potential alternative to the Patlak model of CT perfusion","title_sort":"Evaluation of optimal acquisition delays of DECT iodine maps in pancreatic adenocarcinoma"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1844484378"],"doi":["10.1016/j.heliyon.2023.e14726"]},"physDesc":[{"extent":"12 S."}]} | ||
| SRT | |a SKORNITZKEEVALUATION2023 | ||