Magel2 truncation alters select behavioral and physiological outcomes in a rat model of Schaaf-Yang syndrome

Previous studies in mice have utilized Magel2 gene deletion models to examine the consequences of its absence. We report the generation, molecular validation and phenotypic characterization of a novel rat model with a truncating Magel2 mutation modeling variants associated with Schaaf-Yang syndrome-...

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Hauptverfasser:	Reznik, Derek (VerfasserIn) , Yang, Mingxiao V. (VerfasserIn) , Albelda de la Haza, Pedro (VerfasserIn) , Jain, Antrix (VerfasserIn) , Spanjaard, Melanie (VerfasserIn) , Theiß, Susanne (VerfasserIn) , Schaaf, Christian P. (VerfasserIn) , Malovannaya, Anna (VerfasserIn) , Strong, Theresa V. (VerfasserIn) , Veeraragavan, Surabi (VerfasserIn) , Samaco, Rodney C. (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	February 2023
In:	Disease models & mechanisms Year: 2023, Jahrgang: 16, Heft: 2, Pages: 1-18
ISSN:	1754-8411
DOI:	10.1242/dmm.049829
Online-Zugang:	Verlag, kostenfrei, Volltext: https://doi.org/10.1242/dmm.049829 Verlag, kostenfrei, Volltext: https://journals.biologists.com/dmm/article/16/2/dmm049829/286899/Magel2-truncation-alters-select-behavioral-and
Verfasserangaben:	Derek L. Reznik, Mingxiao V. Yang, Pedro Albelda de la Haza, Antrix Jain, Melanie Spanjaard, Susanne Theiss, Christian P. Schaaf, Anna Malovannaya, Theresa V. Strong, Surabi Veeraragavan and Rodney C. Samaco