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Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group

Recent advances in genomics, proteomics, and biotechnology have provided unprecedented opportunities for translational research and personalized medicine. Human biospecimens and biofluids represent an important resource from which molecular data can be generated to detect and classify injury and to...

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Main Authors: Manley, Geoffrey T. (Author) , Diaz-Arrastia, Ramon (Author) , Brophy, Mary (Author) , Engel, Doortje C. (Author) , Goodman, Clay (Author) , Gwinn, Katrina (Author) , Veenstra, Timothy D. (Author) , Ling, Geoffrey (Author) , Ottens, Andrew K. (Author) , Tortella, Frank (Author) , Hayes, Ronald L. (Author)
Format: Article (Journal)
Language:English
Published: 31 October 2010
In: Archives of physical medicine and rehabilitation
Year: 2010, Volume: 91, Issue: 11, Pages: 1667-1672
ISSN:1532-821X
DOI:10.1016/j.apmr.2010.05.018
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Author Notes:Geoffrey T. Manley, Ramon Diaz-Arrastia, Mary Brophy, Doortje Engel, Clay Goodman, Katrina Gwinn, Timothy D. Veenstra, Geoffrey Ling, Andrew K. Ottens, Frank Tortella, Ronald L. Hayes
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Summary:Recent advances in genomics, proteomics, and biotechnology have provided unprecedented opportunities for translational research and personalized medicine. Human biospecimens and biofluids represent an important resource from which molecular data can be generated to detect and classify injury and to identify molecular mechanisms and therapeutic targets. To date, there has been considerable variability in biospecimen and biofluid collection, storage, and processing in traumatic brain injury (TBI) studies. To realize the full potential of this important resource, standardization and adoption of best practice guidelines are required to insure the quality and consistency of these specimens. The aim of the Biospecimens and Biomarkers Working Group was to provide recommendations for core data elements for TBI research and develop best practice guidelines to standardize the quality and accessibility of these specimens.
Item Description:Gesehen am 04.05.2023
Physical Description:Online Resource
ISSN:1532-821X
DOI:10.1016/j.apmr.2010.05.018

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